Serum and endometrial markers

Yang WC, Wei-Chung Vivian Yang, Wei‐Chung Vivian Yang, Huei‐Wen Chen, Huei-Wen Chen, Heng-Kien Au, Heng‐Kien Au, Au HK, Ching-Wen Chang, Chang CW, Huang CT, Chien-Tsang Huang, Yen YH, Yu-Hsun Yen, Tzeng CR, Chii‐Ruey Tzeng, Chii-Ruey Tzeng
Best practice & research. Clinical obstetrics & gynaecology · 2004 · vol. 18(2) , pp. 305–318 · doi:10.1016/j.bpobgyn.2004.03.003 · PMID:15157644 · W2046565693
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⚙ AI-generated summary by claude@2026-06, 2026-06-23 ⓘ

This paper investigates serum and endometrial markers to understand their role in a specific biomedical context.

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Abstract

Endometriosis is a benign but aggressive disease. It occurs when shed endometrium from the female reproductive tract grows at a site outside the uterus. The physiological changes in endometriosis-abnormal tissue growth, invasion, and adhesion phenomena-are similar to those seen in tumorous tissues. Although the etiology of endometriosis is not well understood, the disease is widely accepted to result from the ectopic implantation of refluxed menstrual tissues. In addition, immunologic changes, genetic factors, and environmental factors might also affect a woman's susceptibility to develop endometriosis. Thus far, laparoscopic examination is required to confirm the presence of endometriosis; there is no reliable marker for its diagnosis. Many studies are therefore focusing on identifying markers for the diagnosis and follow-up of endometriosis. This chapter provides a systematic review of these studies, including recent findings from our group on the identification of molecules, in serum and/or endometrium, which are associated with the development of endometriosis at different stages. From this research, we hope to be able to suggest how to approach the potential markers. The identification of highly sensitive and specific markers of endometriosis should facilitate the development of accurate and non-invasive techniques for diagnosis and prognosis.

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Condition tags

endometriosis

MeSH descriptors

Biomarkers Endometriosis Endometrium Autoantibodies Autoantibodies Biomarkers Biomarkers Cell Adhesion Molecules Cell Adhesion Molecules Cytokines Cytokines Endometriosis Endometriosis Endometrium Female Genetic Predisposition to Disease Growth Substances Growth Substances Humans Matrix Metalloproteinases

Citation neighborhood

Papers in the corpus that this work cites (lower rings, blue) and that cite this one (upper rings, green). Dot size scales with the paper's in-corpus citation count — bigger dot = more influential within the endo/adeno field. Click a dot to open that paper. [ expand to 2 hops ] — adds papers reached through this work's immediate citers/citees. Heavier; up to 60 extra dots.

References (100)

Cited by (35)

Source provenance

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License: CC0 · commercial use OK