Correlación entre valores del marcador Ca-125 con la presencia y severidad de endometriosis pelviana
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This study found that elevated CA-125 levels correlate with the presence and severity of pelvic endometriosis in infertile women undergoing diagnostic laparoscopy.
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Abstract
BACKGROUND: Endometriosis affects at least 15% of infertile women. The diagnosis is made by direct visualization of implants either at laparoscopy or laparotomy. Elevation of plasma CA-125 levels has been associated with the presence of endometriosis. AIM: To search for a correlation between CA-125 and the presence of endometriosis and its severity, among infertile patients requesting a diagnostic laparoscopy. PATIENTS AND METHODS: A total of 117 women were prospectively enrolled in the study between May 2000 and March 2002. A serum sample for CA-125 was taken immediately before surgery and the value obtained was correlated with the presence or absence of endometriosis and the severity of the disease. RESULTS: Sixty nine patients had endometriosis (59%). Patients with severe endometriosis, or grade IV, showed statistically significant higher levels of CA-125 compared to women without endometriosis or with grades I, II or III of the disease. DISCUSSION: The overall sensibility of CA-125 in detecting patients with endometriosis was low, however, it worked better for patients with advanced disease. Considering the rather low cost and simplicity of the test, we believe that it should be included in the evaluation of infertile couples.
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Cited by (8)
- Elevación de los marcadores de estrés oxidativo en pacientes con endometriosis. 2019
- Blood biomarkers for the non-invasive diagnosis of endometriosis 2016
- Diagnostic accuracy of cancer antigen 125 for endometriosis: a systematic review and meta‐analysis 2016
- Correlation between ovarian chocolate cyst and serum carbohydrate antigen 125 level and the effect of ultrasound‐guided interventional sclerotherapy on serum carbohydrate antigen 125 level 2014
- CA 125 serum values in surgically treated endometriosis patients and its relationships with anatomic sites of endometriosis and pregnancy rate 2010
- Endometriosis for the Colorectal Surgeon 2010
- Reccurence of ovarian endometriotic cyst after cystectomy 2009
- Serum and endometrial markers 2004
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- openalex
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