[The concentration of exfoliative adhesion molecules (ICAM-1 and E-Selectin) in serum and peritoneal fluid of women with endometriosis].

Ginekologia polska · 1998 · vol. 69(12) , pp. 1175–8 · PMID:10224799 · W2404268891
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This study found significantly higher serum concentrations of ICAM-1 and E-selectin in women with endometriosis compared to controls, but no significant difference in peritoneal fluid.

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Abstract

It is commonly known that retrograde transport of exfoliative fragments of endometrium to peritoneal cavity during the menstruation is an important factor of the ethiopathogenesis of endometriosis. The mechanism of inplantation of endometrial cells to peritoneal sites still remains unclear. Adhesions molecules are suggested to take part in this process. In our study we tried to establish the concentration of the adhesion molecules (ICAM-1 and E-Selectin) in the sera and peritoneal fluids of women with endometriosis in comparison to the control group. These concentrations were significantly higher in the sera of all patients. We did not find any significant differences between two examined groups although further studies should be carried out.

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Condition tags

endometriosis

MeSH descriptors

Ascitic Fluid Endometriosis Endometriosis E-Selectin Intercellular Adhesion Molecule-1 Uterine Diseases Uterine Diseases Adult Ascitic Fluid Endometriosis E-Selectin Female Humans Intercellular Adhesion Molecule-1 Laparoscopy Laparoscopy Uterine Diseases

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