Growing teratoma syndrome (GTS) is a rare condition classically associated with platinum-based chemotherapy for malignant ovarian germ cell tumors. However, post-treatment findings following ovarian immature teratoma may represent a broader…
OBJECTIVES: Circadian rhythm (CR) is a 24-hour biological cycle regulated by endogenous and environmental factors. Altered CR gene expression has been associated with gestational diabetes mellitus (GDM), potentially affecting vascular regul…
OBJECTIVES: Endometriosis is a widespread gynecological condition characterized by the presence of endometrial like tissue outside the uterine cavity. According to the literature, the frequency of endometriosis in adolescents remains unclea…
OBJECTIVES: Endometriosis presents a multitude of challenges for individuals. Current treatment of the disease is based on pharmacotherapy that aims to relieve pain, improves future fertility, potentially slows disease progression and lesse…
This review article explores the psychological dimension of gynecological disorders in girls and young women, emphasizing the need for interdisciplinary approaches in medical care. Gynecological conditions such as endometriosis, polycystic …
Endometriosis is the presence of endometrial tissue outside the uterine cavity with an accompanying chronic inflammatory process. The etiology of the disease is still not fully understood. An important role is attributed to immune system di…
OBJECTIVES: Endometriosis is a common chronic disease in childbearing women and a major cause of infertility. Our study aimed to identify and validate a novel gene signature for diagnosing endometriosis based on histone-related genes (HRGs)…
Iatrogenic endometriosis, a rare form of endometriosis resulting from surgical interventions, has become increasingly recognized as a complication of cesarean sections. This study examines the development of clear cell carcinoma (CCC) arisi…
OBJECTIVES: Some studies indicate the role of transforming growth factor-beta 1 (TGF-beta 1) in the development of endometriosis. However, the lack is studies assessed its plasma levels as a biomarker of endometrioma. Therefore, this study …
BACKGROUND: Adenomyosis is a uterine disorder commonly associated with painful menstrual cycles, abnormal uterine bleeding, and dyspareunia, which can significantly impact fertility, pregnancy outcomes and overall quality of life. Recent li…
OBJECTIVES: Endometriosis is a prevalent chronic gynecological condition resulting in infertility, and severe pain that strongly deteriorates patients' quality of life. In addition to surgery and pharmacotherapy, there are also other method…
OBJECTIVES: Due to the increasingly faster pace of life and responsibilities, stress has become an integral part of daily life. Every year, numerous social campaigns in the media raise the issue of increasing alcohol consumption. Endometrio…
OBJECTIVES: Endometriosis is a complex, chronic inflammatory disease in which immune system disorders play an important role. Soluble mediators of the immune and inflammatory response, including cytokines, are involved in these processes. T…
OBJECTIVES: This study aimed at assessing the adverse outcomes of pregnancy in women with endometriosis. MATERIAL AND METHODS: The Cochrane, Embase and PubMed databases were searched for identifying the required studies published before Ju…
OBJECTIVES: Though laparoscopic surgery is effective for the treatment of deep endometriosis (DE), postoperative management remains controversial. Dienogest therapy after surgery may improve spontaneous pregnancy rates and decrease the seve…
OBJECTIVES: Endometriosis is a disease that involves the ectopic growth of the endometrial tissue outside the uterine cavity. Its average occurrence is about 10% of women of reproductive age. Making a diagnosis of the disease is commonly lo…
OBJECTIVES: To compare utility of CA125, human epididymis protein 4 (HE4), risk of ovarian malignancy algorithm (ROMA), risk of malignancy index (RMI) and subjective assessment (SA) in preoperative diagnosis of ovarian tumors. MATERIAL AND…