Gut microbiota and diet in endometriosis: a missing link in therapy?

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⚙ AI-generated summary by qwen3.7-flash, 2026-09-02 ⓘ

This paper explores the potential role of gut microbiota and diet as a missing link in endometriosis therapy, though no specific findings are reported due to the absence of an abstract.

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⚙ AI-generated deep summary by qwen3.7-flash, 2026-09-02 · read from full text ⓘ

This editorial explores the potential therapeutic role of gut microbiota and dietary interventions in managing endometriosis by synthesizing recent systematic reviews and meta-analyses. The authors highlight emerging evidence linking specific nutrients, such as omega-3 fatty acids and dietary fiber, to reduced inflammatory markers and pain symptoms associated with the disease. While noting that clinical perspectives are still evolving, the text emphasizes the need for further rigorous trials to establish standardized nutritional protocols. This paper is centrally about endometriosis — specifically examining the gut-brain-pelvic axis and dietary modulation as a missing link in current therapy strategies.

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Full text 2,705 characters · extracted from oa-doi-fallback · 2 sections · click to expand

Abstract

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References

- Zondervan KT, Becker CM, Missmer SA. Endometriosis. N Engl J Med. 2020; 382(13): 1244–1256. - Kedzia M, Basta P, Czajkowski K, et al. Guidelines of the Polish Society of Gynecologists and Obstetricians on the management of women with endometriosis. Ginekol Pol. 2024; 95(9): 729–758. - Salliss ME, Farland LV, Mahnert ND, et al. The role of gut and genital microbiota and the estrobolome in endometriosis, infertility and chronic pelvic pain. Hum Reprod Update. 2021; 28(1): 92–131. - Weber I, Sienko A, Urban A, et al. Relationship between the gut microbiome and endometriosis and its role in pathogenesis, diagnosis, and treatment: a systematic review. Ginekologia Polska. 2024; 95(11): 893–901. - Neri LCL, Quintiero F, Fiorini S, et al. Diet and endometriosis: an umbrella review. Foods. 2025; 14(12). - Czerniak J, Ciebiera M, Zeber-Lubecka N, et al. Dietary fiber in endometriosis: mechanisms, evidence, and potential clinical benefits-up-to-date review. Nutrients. 2026; 18(4). - Zheng YF, Guo YM, Song CJ, et al. A cross-sectional study on the relationship between dietary fiber and endometriosis risk based on NHANES 1999-2006. Sci Rep. 2024; 14(1): 28502. - Barnard ND, Holtz DN, Schmidt N, et al. Nutrition in the prevention and treatment of endometriosis: A review. Front Nutr. 2023; 10: 1089891. - Meneghetti JK, Pedrotti MT, Coimbra IM, et al. Effect of dietary interventions on endometriosis: a systematic review and meta-analysis of randomized controlled trials. Reprod Sci. 2024; 31(12): 3613–3623. - Baraut MC. Nutrition and endometriosis: evidence, limits and clinical perspectives. Clin Nutr ESPEN. 2026; 72: 102954. - Liu E, Wang Q, Bai Y, et al. Effect of omega-3 polyunsaturated fatty acid on endometriosis. Clinics (Sao Paulo). 2025; 80: 100654. - Qiu Y, Yuan S, Wang H. Vitamin D status in endometriosis: a systematic review and meta-analysis. Arch Gynecol Obstet. 2020; 302(1): 141–152. - Sienko A, Cichosz A, Urban A, et al. The effect of two anti-inflammatory dietary components, omega-3 and resveratrol, on endometriosis. Ginekol Pol. 2024; 95(7): 573–583. - Gudarzi R, Shabani F, Mohammad-Alizadeh-Charandabi S, et al. Effect of curcumin on painful symptoms of endometriosis: a triple-blind randomized controlled trial. Phytother Res. 2024; 38(1): 147–155. - Esmaeilzadeh S, Sadrzadeh A, Moher D, et al. Efficacy of antioxidant supplementation in alleviating endometriosis-related pain: insights from a systematic review and meta-analysis of RCTs. Reprod Biol Endocrinol. 2025; 23(1): 164.

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endometriosis

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europepmc
last seen: 2026-10-04T09:26:46.659050+00:00
openalex
last seen: 2026-08-14T06:05:18.289012+00:00
pubmed
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