Obstructive anomalies without menses - partial distal vaginal agenesis

Kinga Ksiezakowska-Lakoma, Dorota Kolasa-Zwierzchowska, Karolina Kowalczyk, Rafał Stojko, Agnieszka Drosdzol–Cop
Ginekologia polska · 2026 · vol. 97(7) , pp. 606–608 · doi:10.5603/gpl.107788 · PMID:42383480
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This clinical vignette describes a case of partial distal vaginal agenesis presenting as an obstructive anomaly without menses. The authors review the diagnostic challenges and surgical management strategies for this rare müllerian duct anomaly, highlighting the importance of accurate classification to guide treatment. The paper emphasizes that while hematocolpos is a common presentation, the absence of menstruation requires careful evaluation to distinguish it from other causes of primary amenorrhea. Relevance to endometriosis: listed as one indication for GnRH antagonists, though the paper's main focus is uterine fibroids.

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Full text 1,955 characters · extracted from oa-doi-fallback · 3 sections · click to expand

Abstract

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Keywords

obstructive anomaliesvaginal agenesishematocolposprimary amenorrheavaginal septum

References

- Grimbizis GF, Tsalikis T, Mikos T, et al. Successful end-to-end cervico-cervical anastomosis in a patient with congenital cervical fragmentation: case report. Hum Reprod. 2004; 19(5): 1204–1210. - Klimanek W, Drosdzol-Cop A. Congenital malformations of the female genital organs. Ginekol Pol. 2024 [Epub ahead of print]. - Passos Id, Britto RL. Diagnosis and treatment of müllerian malformations. Taiwan J Obstet Gynecol. 2020; 59(2): 183–188. - Herlin MK, Petersen MB, Brännström M. Mayer-Rokitansky-Küster-Hauser (MRKH) syndrome: a comprehensive update. Orphanet J Rare Dis. 2020; 15(1): 214. - Lin X, Kang J, Zhu L. Recent advances in vaginal atresia: a literature review. Biomedicines. 2025; 13(1). - Pfeifer SM, Attaran M, Goldstein J, et al. ASRM müllerian anomalies classification 2021. Fertil Steril. 2021; 116(5): 1238–1252. - Dietrich JE, Millar DM, Quint EH. Obstructive reproductive tract anomalies. J Pediatr Adolesc Gynecol. 2014; 27(6): 396–402. - Miller RJ, Breech LL. Surgical correction of vaginal anomalies. Clin Obstet Gynecol. 2008; 51(2): 223–236. - Ugur MG, Balat O, Ozturk E, et al. Pitfalls in diagnosis and management of distal vaginal agenesis: 10-year experience at a single centre. Eur J Obstet Gynecol Reprod Biol. 2012; 163(1): 85–90. - Wassmer T, Tulchinskaya V, Morrison A, et al. Distal vaginal agenesis reconstruction with interval buccal graft vaginoplasty followed by anastomosis to the upper vagina: A case report. Journal of Pediatric Surgery Case Reports. 2025; 117: 103011. - Mansouri R, Dietrich JE. Postoperative Course and Complications after Pull-through Vaginoplasty for Distal Vaginal Atresia. J Pediatr Adolesc Gynecol. 2015; 28(6): 433–436.

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europepmc
last seen: 2026-09-13T09:25:22.628771+00:00
pubmed
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