Role of Eutopic Endometrium in Pelvic Endometriosis

Luiz Carvalho, L. Carvalho, Carvalho L, Sérgio Podgaec, Sergio Podgaec, Bellodi-Privato M, Marta Bellodi-Privato, Marta Bellodi‐Privato, Tommaso Falcone, Falcone T, Maurício Simões Abrão, Mauricio Simões Abrão, Abrão MS
Journal of minimally invasive gynecology · 2011 · vol. 18(4) , pp. 419–427 · doi:10.1016/j.jmig.2011.03.009 · PMID:21620779 · W2019599115
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⚙ AI-generated summary by claude@2026-06, 2026-06-06 ⓘ

This paper investigated the role of the eutopic endometrium in the development and progression of pelvic endometriosis, exploring its cellular and molecular contributions.

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Abstract

Endometriosis is defined as the presence of endometrial tissue outside the uterine cavity and is considered a benign gynecologic condition; however, in some cases, it may be aggressive. The pathogenesis of endometriosis is complex and multifactorial. Despite being one of the most widely studied gynecologic diseases, its pathogenesis remains uncertain. The intrinsic endometrial abnormalities thought to be associated with endometriosis include abnormal expression of genes, modification of endometrial response to hormones such as progesterone; increased nerve density, and oxidative stress. Evaluation of the endometrium in patients with endometriosis is an important line of investigation in the pathophysiology of the disease. It has been suggested that investigation of eutopic endometrium may help to achieve this goal. Presented herein is a literature review and a comprehensive evaluation of the role of eutopic endometrium in pelvic endometriosis. Clinical correlations of the disease are highlighted, with the objective of understanding the role of eutopic endometrium in endometriosis.

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Condition tags

endometriosis

MeSH descriptors

Endometriosis Endometriosis Endometrium Endometrium Pelvis Endometriosis Endometrium Female Humans

Citation neighborhood

Papers in the corpus that this work cites (lower rings, blue) and that cite this one (upper rings, green). Dot size scales with the paper's in-corpus citation count — bigger dot = more influential within the endo/adeno field. Click a dot to open that paper. [ expand to 2 hops ] — adds papers reached through this work's immediate citers/citees. Heavier; up to 60 extra dots.

References (100)

Cited by (50)

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europepmc
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License: CC0 · commercial use OK