Steroid Receptors in the Uterus: Implications in Endometriosis

Paraskevi Moutsatsou, P Moutsatsou, C E Sekeris
Annals of the New York Academy of Sciences · 2003 · vol. 997(1) , pp. 209–222 · doi:10.1196/annals.1290.024 · PMID:14644828 · W2059583173
review OA: closed CC0 ⤵ 14 in-corpus citations
View on OpenAlex View on PubMed View at publisher

Abstract

Receptor proteins for estrogens, progesterone, androgens, and glucocorticoids have been detected in the various cell types of the uterus. Reference is made to the genes encoding these receptors, to the structure of the receptor proteins, and their functional domains. The mode of action of steroid hormones by gene activation, through their cognate receptors, and by nongenomic effects is briefly presented. The role of the steroid receptors in uterine physiology and the significance of the use of steroid receptor knock-out animals in delineating the in vivo action of the hormones is discussed. Recent results on the possible correlation of steroid receptor gene polymorphisms and of quantitative and qualitative changes in the receptor proteins to the etiopathology of endometriosis are reviewed.

My notes (saved in your browser only)

Condition tags

endometriosis

MeSH descriptors

Endometriosis Receptors, Steroid Uterus Binding Sites Biological Transport Endometriosis Endometriosis Female Humans Prognosis Receptors, Androgen Receptors, Androgen Receptors, Estrogen Receptors, Estrogen Receptors, Glucocorticoid Receptors, Glucocorticoid Receptors, Progesterone Receptors, Progesterone Receptors, Steroid Risk Assessment

Citation neighborhood

Papers in the corpus that this work cites (lower rings, blue) and that cite this one (upper rings, green). Dot size scales with the paper's in-corpus citation count — bigger dot = more influential within the endo/adeno field. Click a dot to open that paper. [ expand to 2 hops ] — adds papers reached through this work's immediate citers/citees. Heavier; up to 60 extra dots.

References (90)

Cited by (14)

Source provenance

europepmc
last seen: 2026-06-11T06:19:48.454388+00:00
openalex
last seen: 2026-06-10T17:14:06.276822+00:00
pubmed
last seen: 2026-05-13T22:12:44.121522+00:00
License: CC0 · commercial use OK