Oxidative stress status in normal ovarian cortex surrounding ovarian endometriosis

Matsuzaki S, Sachiko Matsuzaki, Benoit Schubert, B. Schubert
Fertility and sterility · 2009 · vol. 93(7) , pp. 2431–2432 · doi:10.1016/j.fertnstert.2009.08.068 · PMID:19819438 · W2114836456
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This study investigated oxidative stress markers in normal ovarian cortex adjacent to endometriosis lesions.

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Abstract

Expression levels of 8-hydroxydeoxyguanosine, a sensitive indicator of DNA damage resulting from oxidative stress, were significantly higher in samples of normal ovarian cortex surrounding endometriotic cysts when compared with ovarian cortex surrounding dermoid and serous ovarian cysts. These findings suggest that the normal ovarian cortex surrounding endometriotic tissues is more severely affected by oxidative stress than ovarian cortex adjacent to other benign ovarian cysts.

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Condition tags

endometriosis

MeSH descriptors

Endometriosis Ovarian Diseases Ovary Oxidative Stress Oxidative Stress Oxidative Stress 8-Hydroxy-2'-Deoxyguanosine Adolescent Adult Case-Control Studies Deoxyguanosine Deoxyguanosine Deoxyguanosine Deoxyguanosine DNA Damage DNA Damage Endometriosis Endometriosis Endometriosis Female

Citation neighborhood

Papers in the corpus that this work cites (lower rings, blue) and that cite this one (upper rings, green). Dot size scales with the paper's in-corpus citation count — bigger dot = more influential within the endo/adeno field. Click a dot to open that paper. [ expand to 2 hops ] — adds papers reached through this work's immediate citers/citees. Heavier; up to 60 extra dots.

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Cited by (50)

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