Growth mechanisms of endometriotic cells in implanted places: a review

Jiang QY, Qiao-Ying Jiang, Qiaoying Jiang, Rui-Jin Wu, Ruijin Wu, Wu RJ
Gynecological endocrinology : the official journal of the International Society of Gynecological Endocrinology · 2012 · vol. 28(7) , pp. 562–567 · doi:10.3109/09513590.2011.650662 · PMID:22296665 · W2038203406
Review OA: closed CC0 ⤵ 53 in-corpus citations
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This review summarizes recent research on the adhesion, invasion, angiogenesis, proliferation, apoptosis, and immune molecule variations involved in endometriotic cell growth at implanted sites.

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Abstract

Endometriosis is a common gynecological disease defined by extrauterine growth of endometrial glands and stroma. A variety of theories have been proposed to account for the pathogenesis of this disease, including retrograde transplantation theory, metaplasia of coelomic epithelium, hematogenic and lymphogenic spread, and remnants of the Mŭllerian duct. However, the etiopathology of endometriosis is still obscure. In this article, we aim to summarize recent researches concerning the growth mechanisms of endometriotic cells in implanted sites systematically, including the adhesion, invasion, angiogenesis, proliferation, apoptosis of endometriotic cells, variations of the immune molecules and endometriotic cells themselves, which may provide clues for future researches in the pathogenesis of endometriosis.

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Condition tags

endometriosis

MeSH descriptors

Cell Growth Processes Cell Growth Processes Disease Models, Animal Disease Models, Animal Endometriosis Endometrium Animals Animals Apoptosis Apoptosis Cell Adhesion Cell Adhesion Cell Movement Cell Movement Cell Proliferation Cell Proliferation Endometriosis Endometriosis Endometriosis Endometriosis

Citation neighborhood (2-hop)

Papers in the corpus that this work cites (lower rings, blue) and that cite this one (upper rings, green). Dot size scales with the paper's in-corpus citation count — bigger dot = more influential within the endo/adeno field. Click a dot to open that paper. Outer rings show 2-hop neighbours — papers reached through the immediate citers/citees. [ collapse to 1-hop ]

References (69)

Cited by (50)

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License: CC0 · commercial use OK