Endometriosis and Endometriosis-Associated Tumors

Endometriosis is a chronic gynecologic disorder that affects ~10% of adolescent girls and premenopausal women. The condition, classically defined as the presence of endometrial glands and stroma outside of the uterine cavity, is multifactorial and highly recurrent, and causes considerable morbidities that can significantly diminish the quality of life of affected women. The disease is linked to immune dysfunctions, infertility, and increased risk for ovarian and other cancers. The histological diagnosis of endometriosis, while typically uncomplicated, may be compromised by the heterogeneity of the endometriotic foci which can manifest a spectrum of lesions with distinct and atypical features of stromal and glandular components. Moreover, signs and symptoms of endometriosis remain nonspecific and there is a current lack of predictive noninvasive markers. This chapter aims to provide current understanding of the etiology, pathogenesis, and clinicopathologic features of endometriosis and to highlight the remaining challenges clinicians and pathologists face in the diagnosis, management of symptoms, and provision of care in women with this condition. Access this chapter Tax calculation will be finalised at checkout Purchases are for personal use only Similar content being viewed by others

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(eds) Gynecologic and Obstetric Pathology, Volume 2. Springer, Singapore. https://doi.org/10.1007/978-981-13-3019-3_12 Download citation DOI: https://doi.org/10.1007/978-981-13-3019-3_12 Published: Publisher Name: Springer, Singapore Print ISBN: 978-981-13-3018-6 Online ISBN: 978-981-13-3019-3 eBook Packages: MedicineMedicine (R0)