Endometriosis: Correlation between histologic and visual findings at laparoscopy

A J Walter, Andrew J. Walter, Walter AJ, Hentz JG, J G Hentz, Joseph G. Hentz, P M Magtibay, Magtibay PM, Paul M. Magtibay, Jeffrey L. Cornella, J L Cornella, Cornella JL, Magrina JF, J F Magrina
American Journal of Obstetrics and Gynecology · 2001 · vol. 184(7) , pp. 1407–1413 · doi:10.1067/mob.2001.115747 · PMID:11408860 · W2069542691
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⚙ AI-generated summary by claude@2026-06, 2026-06-08 ⓘ

This study investigated the relationship between visual observations made during laparoscopy and histological findings in patients with endometriosis.

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Abstract

ObjectiveThe purpose of this study was to correlate the diagnosis of endometriosis on the basis of visualization at laparoscopy with the pathologic diagnosis.Study designA prospective study of 44 patients undergoing laparoscopy for the evaluation of chronic pelvic pain was carried out. All areas suggestive of endometriosis were excised and examined pathologically. Peritoneal biopsy specimens were obtained from areas of normal-appearing peritoneum to rule out microscopic endometriosis. All lesions were identified by anatomic site. Visual and histologic American Fertility Society scores were compared. The positive predictive value, sensitivity, negative predictive value, and specificity were determined for visually identified endometriosis versus the histologic correlate.ResultsThe mean prevalence of abnormalities visually consistent with endometriosis was 36%, with 18% confirmed histologically. The positive predictive value was 45%; sensitivity, 97%; negative predictive value, 99%; and specificity, 77%; for visual versus histologic diagnosis of endometriosis. Thirty-six percent of the diagnoses were downstaged on the basis of histologic findings.ConclusionA diagnosis of endometriosis should be established only after histologic confirmation.

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Condition tags

endometriosis

MeSH descriptors

Endometriosis Laparoscopy Adolescent Adult Endometriosis Endometriosis Female Humans Middle Aged Predictive Value of Tests Prevalence Prospective Studies Sensitivity and Specificity

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