American journal of obstetrics and gynecology

BACKGROUND: Deep infiltrating endometriosis predominantly affects the posterior pelvic compartment and often requires complex surgical procedures, which are associated with a significant risk of postoperative complications. Limited evidence…

BACKGROUND: Persons diagnosed with endometriosis report deleterious effects to their physical, psychological, and relational well-being. While some couples state that these challenges extend beyond the person in pain to also affect their pa…

BACKGROUND: Women with endometriosis and adenomyosis have an increased risk of age-dependent diseases such as cardiovascular disease and cancer. Whether this reflects differences in biological age is unknown. OBJECTIVE: To compare the epig…

BACKGROUND: Understanding of the impact of endometriosis on adverse early pregnancy outcomes has evolved in recent decades and has been partly attributed to endocrine dysfunction and chronic inflammation. However, data from population-based…

Uterine fibroids (leiomyomas or myomas) are a major issue for individuals with a uterus as well as a disease with profound disparities for Black/African American (Black) individuals. These disparities have roots in early gynecologic practic…

BackgroundAmong patients undergoing hysterectomy for benign indications, Black patients experience higher rates of perioperative complications across both abdominal and minimally invasive surgical routes. This disparity persists after adjus…

BACKGROUND: Endometriosis is a chronic, gynecologic condition in which tissue similar to the lining of the uterus implants throughout the body. Women with endometriosis have a higher prevalence of infertility and a greater risk of early nat…

OBJECTIVE: Data on long-term outcomes of surgical management of rectal endometriosis are scarce and generally provided by cohort studies where choice of surgical technique is based on various uncontrolled factors with significant lost-to-fo…

BACKGROUND: Postoperative pain following laparoscopic surgery can delay recovery and increase opioid use. Lower insufflation pressures have been consistently shown to reduce pain in general surgery procedures, but their impact in gynecologi…

OBJECTIVE: To systematically review and quantify the impact of adenomyosis on maternal, neonatal, and obstetric outcomes. DATA SOURCES: A comprehensive, unrestricted search was conducted in MEDLINE, Scopus, Embase, Literatura Latino-Americ…

Cesarean delivery, one of the most common surgeries performed worldwide, carries the risk of complications. These complications affect both mothers and newborns, but in this review, only maternal complications will be addressed. Clinical si…

ObjectivesDespite many available treatments for female chronic pelvic pain (FCPP), there is limited patient success, engagement, or compliance with therapy. No current methods allow providers to effectively collect and integrate patient per…

BACKGROUND: It is unknown to what extent the surgical management of endometriosis occurs in the outpatient settings and which factors are associated with ambulatory vs inpatient surgical care. OBJECTIVE: The objective of this study was to …

BackgroundPolycystic ovary syndrome is a common endocrine disorder, characterized by oligomenorrhea and androgen excess. Only a few studies have addressed the natural history of menstrual cycles among women with polycystic ovary syndrome an…

In 1995, Morris first described cesarean scar defect as an "isthmocele" by macroscopy following hysterectomy in women with prior cesarean delivery. Cesarean scar defect is associated with gynecological symptoms such as abnormal uterine blee…

BACKGROUND: The cesarean scar niche, a consequence of incomplete wound healing, can lead to gynecological complications and affect future pregnancies. While internal niches have been well-studied, external and bidirectional niches are also …

BackgroundDespite widespread agreement that high-tone pelvic floor dysfunction is highly prevalent among women with pelvic pain, there is no consensus regarding standardized assessment strategy or diagnostic criteria. Furthermore, there are…

Single-cell technologies are expanding our understanding of endometriosis and adenomyosis, which are sister disorders of the uterine endometrium that contain similar complements of lesion cell types but in different locations-outside and in…

BackgroundFertility success among mixed-sex couples often depends on frequency and timing of sexual intercourse, yet little research has evaluated the association between preconception sexual function and time-to-pregnancy.ObjectiveTo evalu…

BACKGROUND: Adenomyosis is a uterine disorder closely linked to infertility and adverse pregnancy outcomes. Despite its clinical significance, the mechanisms by which adenomyosis impairs embryo implantation and perinatal outcomes remain inc…

BackgroundMenstrual cycle characteristics are potential indicators of hormonal exposures and may also signal cardiovascular disease risk factors, both of which are relevant to cognitive health. However, there is scarce epidemiological evide…