Brief Review of Endometriosis and the Role of Trace Elements

Ida Osuchowska-Grochowska, Eliza Blicharska, Marek Gogacz, Agata Nogalska, Izabela Winkler, Agnieszka Szopa, Halina Ekiert, Barbara Tymczyna-Borowicz, Barbara Tymczyna, Mansur Rahnama, Cezary Grochowski
International journal of molecular sciences · 2021 · vol. 22(20) , pp. 11098 · doi:10.3390/ijms222011098 · PMID:34681755 · W3205039963
review OA: gold CC0 ⤵ 9 in-corpus citations
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⚙ AI-generated summary by claude@2026-06, 2026-06-07 ⓘ

This review examines the potential role of trace elements, particularly in endometrial-like implants, as a contributing factor to the oxidative stress and inflammation observed in endometriosis.

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Abstract

Endometriosis is a chronic, estrogen-dependent, inflammatory condition that is defined as the presence of endometrial glands and stroma outside the uterine cavity. Despite the progress in research into the mechanisms leading to the development of endometriosis, its cause has not yet been established. It seems to be possible that the formation of oxidative stress may be one of the main causes of the development of endometriosis. There is much research that studies the potential role of trace elements in the appearance of endometrial-like lesions. Most studies focus on assessing the content of selected trace elements in the blood, urine, or peritoneal fluid in women with endometriosis. Meanwhile, little is known about the content of these elements in endometrial-like implants, which may be helpful in developing the theory of endometriosis. Investigations that are more comprehensive are needed to confirm a hypothesis that some trace elements play a role in the pathomechanism of endometriosis.

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Condition tags

mesh:D004715endometriosis

MeSH descriptors

Biomarkers Endometriosis Trace Elements Animals Ascitic Fluid Ascitic Fluid Biomarkers Endometriosis Endometriosis Endometriosis Female Humans Trace Elements Trace Elements Trace Elements

Citation neighborhood

Papers in the corpus that this work cites (lower rings, blue) and that cite this one (upper rings, green). Dot size scales with the paper's in-corpus citation count — bigger dot = more influential within the endo/adeno field. Click a dot to open that paper. [ expand to 2 hops ] — adds papers reached through this work's immediate citers/citees. Heavier; up to 60 extra dots.

References (100)

Cited by (9)

Source provenance

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