Combination of transvaginal sonography and clinical examination for preoperative diagnosis of pelvic endometriosis

Gernot Hudelist, G Hudelist, K H Oberwinkler, KH Oberwinkler, C F Singer, CF Singer, F Tuttlies, G Rauter, Olga Maria Schimidt Ritter, O Ritter, J Keckstein
Human Reproduction · 2009 · vol. 24(5) , pp. 1018–1024 · doi:10.1093/humrep/dep013 · PMID:19202143 · W2162793918
article OA: bronze CC0 ⤵ 136 in-corpus citations
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Transvaginal sonography combined with clinical examination accurately diagnosed pelvic endometriosis in patients with suspected disease, particularly for ovaries, vagina, rectum, and uterosacral ligaments.

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Abstract

BACKGROUND: The aim of the present study was to evaluate the accuracy of routine clinical examination (per vaginam, PV) combined with transvaginal sonography (TVS) for presurgical, non-invasive diagnosis of endometriosis. METHODS: Two-hundred women with symptoms suggestive of endometriosis were prospectively assessed by PV and TVS prior to laparoscopy and radical resection of disease and histological confirmation. RESULTS: Prevalence of endometriosis on the right/left (r/l) ovary, r/l uterosacral ligament (USL), pouch of Douglas (POD), vagina, bladder, rectovaginal space (RVS) and rectum was 12%, 13%, 12%, 22%, 15%, 11%, 2%, 4% and 24%. Sensitivities, specificities, positive and negative predictive values and positive and negative likelihood ratios for combined use of TVS and PV resulted in 96/100%, 100/99%, 100/93%, 93/100% and -;0.04/87.0;- for the r/l ovarian endometriosis; 67/84%, 97/86%, 73/62%, 96/95% and 19.56;0.35/5.97;0.19 for the r/l USL disease; 87%, 98%, 90%, 98% and 49.11;0.14 for involvement of the POD; 82%, 99%, 95%, 98% and 145.64;0.18 for vaginal endometriosis; 88%, 99%, 78%, 99% and 84.0;0.13 for endometriosis of the RVS; 75%, 98%, 50%, 99% and 49.0;0.25 for bladder involvement and 96%, 98%, 94%, 99% and 48.56;0.04 for rectal endometriosis. CONCLUSIONS: The combination of PV and TVS accurately predicts the presence of endometriosis affecting the ovaries, vagina, rectum, USL, RVS and POD in patients with suspected endometriosis. We suggest the routine combination of PV and TVS as an essential part of the standard primary assessment of pelvic pain patients with suspected endometriosis.

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Condition tags

endometriosischronic_pelvic_pain

MeSH descriptors

Endometriosis Pelvic Pain Ultrasonography Adolescent Adult Endometriosis Endometriosis Endometriosis Female Humans Middle Aged Pelvic Pain Pelvic Pain Pelvic Pain Predictive Value of Tests Prevalence Ultrasonography

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