Guideline No. 449: Diagnosis and Impact of Endometriosis - A Canadian Guideline
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This Canadian guideline provides recommendations for the diagnosis and impact of endometriosis, aiming to improve patient care and outcomes.
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Abstract
OBJECTIVE: To provide a contemporary approach to the understanding of the impact and methods for the diagnosis of endometriosis in Canada.
TARGET POPULATION: Individuals, families, communities, health care providers, and health care administrators who are affected by, care for patients with, or manage delivery of services for endometriosis.
OPTIONS: The diagnosis of endometriosis is facilitated by a detailed history, examination, and imaging tests with providers who are experienced in endometriosis care. Surgical evaluation with pathology confirms a diagnosis of endometriosis; however, it is not required for those whose diagnosis was confirmed with imaging.
OUTCOMES: There is a need to address earlier recognition of endometriosis to facilitate timely access to care and support. Education directed at the public, affected individuals and families, health care providers, and health care administrators are essential to reduce delays in diagnosis and treatment.
BENEFITS, HARMS, AND COSTS: Increased awareness and education about the impact and approach to diagnosis may support timely access to care for patients and families affected by endometriosis. Earlier and appropriate care may support a reduced health care system burden; however, improved clinical evaluation may require initial investments.
EVIDENCE: Each section was reviewed with a unique search strategy representative of the evidence available in the literature related to the area of focus. The literature searches for each section of this guideline are listed in Appendix A and include information from published systematic reviews described in the text.
VALIDATION METHODS: The recommendations were developed following two rounds of review by a national expert panel through an iterative 2-year consensus process. Further details on the process are shared in Appendix B. The authors rated the quality of evidence and strength of recommendations using the Grading of Recommendations Assessment, Development and Evaluation (GRADE) approach. See Appendix C (Table C1 for definitions and Table C2 for interpretations of strong and conditional recommendations).
INTENDED AUDIENCE: This guideline is intended to support health care providers and policymakers involved in the care of those impacted by endometriosis and the systems required to support them.
TWEETABLE ABSTRACT: Endometriosis impact and diagnosis updated guidelines for Canadian health care providers and policymakers.
SUMMARY STATEMENTS: RECOMMENDATIONS.
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- The endometriosis diagnosis process within the National Health Service in the United Kingdom: an examination of key factors associated with psychological distress 2026
- Lignes directrices de pratique clinique n° 468 : Prise en charge clinique de l'endométriose 2026
- Endometriosis and Chronic Endometritis: Shared Mechanisms, Diagnostic Challenges, and Clinical Implications in Infertility 2026
- Biosensors and enabling analytical technologies for in vitro fertilization: current trends and emerging applications 2026
- Progestagens for pain symptoms associated with endometriosis 2025
- Endometriosis 2025
- Endometriosis Clinical and Surgical Care During the COVID-19 Pandemic: A Comparison of Virtual-Only Care to Virtual and In-Person Care Combined 2025
- Steroid Metabolome Profiling Identifies a Unique Androgen Hormone Signature Associated with Endometriosis 2025
- Understanding Dysmenorrhea in Individuals with Polycystic Ovary Morphology (PCOM) 2025
- Interobserver Reproducibility of Two Endometriosis Scoring Systems: A Multicentre Observational Prospective Study 2025
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- The Role of Ultrasound in the Evolving Landscape of Precision Imaging of Endometriosis 2025
- Endometriosis: pathophysiology and the potential role of diet 2025
- Global, regional, and national burden of endometriosis among women of childbearing age from 1990 to 2021: a cross-sectional analysis from the 2021 global burden of disease study 2025
- Quantification of Protein Biomarkers in SonoPODography Fluid Using Single Molecule Arrays for Endometriosis 2025
- Endometriosis as a Risk Factor for Ischemic and Hemorrhagic Stroke: A Population-Based Cohort Study 2025
- Evaluation and Treatment of Chronic Pelvic Pain 2025
- Comprehensive endometriosis care: a modern multimodal approach for the treatment of pelvic pain and endometriosis 2024
- Endometriosis: recent advances that could accelerate diagnosis and improve care 2024
- Endometriosis: Improvements and challenges in diagnosis and symptom management 2024
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