Progression of Endometriosis in Non-medically Managed Adolescents: A Case Series

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This case series describes the progression of endometriosis over time in adolescents who did not receive medical management for their condition.

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Abstract

BackgroundEndometriosis is considered a progressive disease that can cause chronic pelvic pain and infertility. A combined medical-surgical approach is the best method to slow the progression of endometriosis. Adolescents who are not maintained on a medical regimen postoperatively may be at risk for disease progression.CasesThis is a case series of three adolescent patients who presented at 13 to 16 years of age with complaint of severe pelvic pain and were diagnosed with stage 1 endometriosis at the time of laparoscopy. They were then prescribed menstrual suppressive therapy but did not remain compliant with their regimens.Results and conclusionsEach patient returned to the operating room and underwent a second laparoscopy which revealed that each patient's disease had progressed to a higher stage. Without combined surgical-medical management, disease worsens, and places patients at risk for severe chronic pelvic pain as well as infertility.

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Condition tags

endometriosischronic_pelvic_pain

MeSH descriptors

Disease Progression Endometriosis Patient Compliance Adolescent Anti-Inflammatory Agents, Non-Steroidal Anti-Inflammatory Agents, Non-Steroidal Contraceptives, Oral, Hormonal Contraceptives, Oral, Hormonal Endometriosis Endometriosis Endometriosis Female Humans Laparoscopy Pelvic Pain Pelvic Pain Pelvic Pain

Citation neighborhood

Papers in the corpus that this work cites (lower rings, blue) and that cite this one (upper rings, green). Dot size scales with the paper's in-corpus citation count — bigger dot = more influential within the endo/adeno field. Click a dot to open that paper. [ expand to 2 hops ] — adds papers reached through this work's immediate citers/citees. Heavier; up to 60 extra dots.

References (22)

Cited by (50)

Source provenance

europepmc
last seen: 2026-08-01T06:07:04.264727+00:00
openalex
last seen: 2026-06-10T17:14:06.276822+00:00
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License: CC0 · commercial use OK