Differences in characteristics among 1,000 women with endometriosis based on extent of disease

Sinaii N, Ninet Sinaii, Katherine Plumb, Plumb K, Cotton L, Louise Cotton, Ann Lambert, Lambert A, Kennedy S, Stephen Kennedy, Krina Zondervan, Krina T. Zondervan, Pamela Stratton, Stratton P
Fertility and sterility · 2007 · vol. 89(3) , pp. 538–545 · doi:10.1016/j.fertnstert.2007.03.069 · PMID:17498711 · PMC2939902 · W1976254258
article OA: bronze CC0 ⤵ 211 in-corpus citations
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⚙ AI-generated summary by claude@2026-06, 2026-06-08 ⓘ

This study examined the characteristics of 1,000 women with endometriosis and identified differences based on the extent of their disease.

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Abstract

ObjectiveTo determine the relationship between disease severity and patient characteristics in endometriosis.DesignCross-sectional study of self-reported survey data.SettingAcademic research setting.Patient(s)One thousand women in the Oxford Endometriosis Gene (OXEGENE) study.Intervention(s)None.Main outcome measure(s)Participants were assigned to one of two groups with predominantly revised AFS stage I-II (group I, n = 423) or III-IV disease (group II, n = 517). Their characteristics were compared by disease extent.Result(s)Most participants were white (96%) and of reproductive age (81%). Women in group I were significantly younger on entering the study (39.9 +/- 0.5 vs. 44.5 +/- 0.4 years). Overall time to diagnosis did not differ between groups. The most common symptoms leading to a diagnosis were dysmenorrhea (79%) and pelvic pain (69%). In group II, subfertility (21.5% vs. 30.0%) and an ovarian mass (7.3% vs. 29.4%) more commonly led to a diagnosis, whereas dyspareunia (51.1% vs. 39.5%) was significantly more common in group I. Subfertility (41.5% vs. 53.4%) remained more common in group II throughout reproductive life, although birth and miscarriage rates were similar.Conclusion(s)Pelvic pain is common to all with endometriosis and those with more extensive disease report higher rates of subfertility. Remarkably, the time to diagnosis was similar among women.

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Condition tags

dysmenorrheadyspareuniaendometriosischronic_pelvic_pain

MeSH descriptors

Abortion, Spontaneous Dysmenorrhea Dyspareunia Endometriosis Infertility, Female Ovarian Neoplasms Pelvic Pain Abortion, Spontaneous Abortion, Spontaneous Abortion, Therapeutic Abortion, Therapeutic Adult Age Factors Australia Australia Birth Rate Canada Canada Cross-Sectional Studies Dysmenorrhea

Citation neighborhood

Papers in the corpus that this work cites (lower rings, blue) and that cite this one (upper rings, green). Dot size scales with the paper's in-corpus citation count — bigger dot = more influential within the endo/adeno field. Click a dot to open that paper. [ expand to 2 hops ] — adds papers reached through this work's immediate citers/citees. Heavier; up to 60 extra dots.

References (34)

Cited by (50)

Source provenance

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