Endometriosis Unveiled: Innovations in Diagnosis and Management of Endometriosis

Hannah Millimet, A F Lee, Courtney Lim, C Allaire, Sawsan As-Sanie
In: Clinical Obstetrics & Gynecology · 2026 · doi:10.1097/grf.0000000000001045 · W7168135010
article OA: closed CC0
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Abstract

Endometriosis is a chronic inflammatory condition that can result in chronic pain through complex nociceptive, neuropathic, and nociplastic pathways. This article provides a comprehensive background on endometriosis as well as future directions in diagnosis and management. The diagnosis of endometriosis is explored, including novel imaging techniques, biomarkers, and the integration of artificial intelligence. The medical management of endometriosis is reviewed, including a focus on new nonhormonal treatment options. Surgical treatments are reviewed along with surgical outcomes. We discuss nonpharmaceutical and behavioral interventions with growing interest. Finally, this article reviews future directions in endometriosis care, including precision medicine and AI.

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