Determinants of short term recurrence rate of endometriosis

Fabio Parazzini, Bertulessi C, C Bertulessi, Carlo Bertulessi, Andrea Pasini, Pasini A, M. Rosati, Maurizio Rosati, Rosati M, Di Stefano F, Fabio Di Stefano, Shonauer S, Sergio Shonauer, Mario Vicino, Lorenzo Aguzzoli, Trossarelli GF, Gian Franco Trossarelli, Massobrio M, Mario Massobrio, Bracco G, G Bracco, Gianluca Bracco, A Perino, Antonio Perino, Moroni S, Simona Moroni, Paolo Beretta, P Beretta, Beretta P, Gruppo Italiano di Studio Endometriosi
European journal of obstetrics, gynecology, and reproductive biology · 2005 · vol. 121(2) , pp. 216–219 · doi:10.1016/j.ejogrb.2004.11.033 · PMID:16054965 · W2143855438
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This study investigated factors associated with the short-term recurrence rate of endometriosis following treatment.

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Abstract

ObjectiveTo analyse the frequency and the determinants of recurrence rate of clinically detectable endometriosis.Study designProspective cohort multicenter study. Eligible for the study were all women observed for the first time during the period January-June 1998 at the participating centres with a laparoscopically confirmed first diagnosis of endometriosis. After diagnosis, patients were treated according to standard care of each centre and desire for pregnancy. The protocol required all women to be followed up at the centre each year for 2 years with a clinical examination, an ultrasound pelvic examination and a CA125 assay, unless pregnancy occurred. Second look laparoscopy was performed on a clinical basis.ResultsA total of 311 women (median age 36 years) entered the study. The two-year recurrence rate was 5.7% among cases stage I-II and 14.4% among stage III-IV (chi(1)2 adjusted for indication for surgery, p 30, but this finding was not statistically significant.ConclusionThe recurrence rate of clinically detectable endometriosis tends to be higher in older women with advanced stages of the disease and lower in women with infertility.

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Condition tags

endometriosis

MeSH descriptors

Endometriosis Endometriosis Adult Cohort Studies Endometriosis Endometriosis Female Humans Italy Italy Prospective Studies Recurrence

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