Recurrence in Deep Infiltrating Endometriosis: A Systematic Review of the Literature

Manuel Maria Ianieri, Daniele Mautone, Mautone D, Marcello Ceccaroni
Journal of minimally invasive gynecology · 2018 · vol. 25(5) , pp. 786–793 · doi:10.1016/j.jmig.2017.12.025 · PMID:29357317 · W2790313896
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This systematic review synthesizes existing literature to identify risk factors and predictors of recurrence in patients diagnosed with deep infiltrating endometriosis.

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Abstract

Deep infiltrative endometriosis (DIE) is an enigmatic disease that typically impacts the rectovaginal septum, uterosacral ligaments, pararectal space, and vesicouterine fold but can involve the rectum, sigma, ileum, ureters, diaphragm, and other less common sites. Surgery is the treatment of choice because medical management alone commonly fails in controlling the symptoms although recurrence is very high after surgical treatment. The goal of the current study was to review recurrence rates and identify risk factors related to recurrence after surgery for DIE. The review involved searching the Cochrane Library, PubMed, and Google Scholar for relevant articles in accordance with the study's inclusion criteria; 45 studies were considered suitable. The results showed a wide heterogeneity regarding DIE recurrence because of inconsistent recurrence definitions and follow-up length. Younger age and high body mass index were found to be risk factors for DIE recurrence. Lack of complete surgical excision was another independent risk factor for recurrence of disease. In conclusion, there is a need for prospective studies and a more homogeneous standard for surgical treatment of DIE.

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Condition tags

endometriosisdie_deep_infiltrating

MeSH descriptors

Endometriosis Intestinal Diseases Endometriosis Endometriosis Female Humans Intestinal Diseases Intestinal Diseases Laparoscopy Laparoscopy Peritoneal Diseases Peritoneal Diseases Rectum Rectum Recurrence Risk Factors Vagina Vagina

Citation neighborhood

Papers in the corpus that this work cites (lower rings, blue) and that cite this one (upper rings, green). Dot size scales with the paper's in-corpus citation count — bigger dot = more influential within the endo/adeno field. Click a dot to open that paper. [ expand to 2 hops ] — adds papers reached through this work's immediate citers/citees. Heavier; up to 60 extra dots.

References (64)

Cited by (50)

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