Retroperitoneal endometriosis in postmenopausal woman causing deep vein thrombosis: case report and review of the literature

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AI-generated summary by claude@2026-06, 2026-06-12

This case report details a postmenopausal woman who presented with deep vein thrombosis due to retroperitoneal endometriosis causing iliac vein compression.

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AI-generated deep summary by claude@2026-06, 2026-06-12 · read from full text

This paper reports a 63-year-old postmenopausal woman with six weeks of abdominal pain and left leg pain and swelling, in whom imaging showed a retroperitoneal mass compressing the left iliac vein and associated with deep vein thrombosis. The authors performed laparotomy with removal of the pelvic masses, and histology confirmed endometriosis; follow-up imaging about a month later showed a considerable decrease in thrombosis of the homolateral external iliac veins after postoperative management. The major caveat stated is that endometriosis is uncommon after menopause and neoplastic transformation of endometrium must be excluded, so the diagnosis requires careful consideration. This paper is centrally about endometriosis — it presents a retroperitoneal endometriosis case in a postmenopausal woman causing deep vein thrombosis and reviews related literature.

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Abstract

Endometriosis is an uncommon disease in postmenopausal women (PMW), ranging from 2% to 5% of cases, and it is very important to exclude neoplastic transformation of the endometrium. The authors would like to introduce the case of a 63-year-old overweight patient with abdominal pain associated to pain and swelling of the left inferior limb occurring for approximately six weeks. The CT X-ray of the abdomen revealed the presence of a retroperitoneal mass causing deep vein thrombosis because of extrinsic compression of the left iliac vein. Following removal of the pelvic masses with laparotomy, the histological exam revealed an endometriosis. The CT X-ray carried out after a month postoperatively revealed the root canal treatment of the left femoral vein with a considerable decrease of the thrombosis of homolateral external iliac veins. Despite the endometriosis, it is uncommon in women who have reached menopause and must be considered in the differential diagnosis of pelvic masses.
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Abstract

Endometriosis is an uncommon disease in postmenopausal women (PMW), ranging from 2% to 5% of cases, and it is very important to exclude neoplastic transformation of the endometrium. The authors would like to introduce the case of a 63-year-old overweight patient with abdominal pain associated to pain and swelling of the left inferior limb occurring for approximately six weeks. The CT Xray of the abdomen revealed the presence of a retroperitoneal mass causing deep vein thrombosis because of extrinsic compression of the left iliac vein. Following removal of the pelvic masses with laparotomy, the histological exam revealed an endometriosis. The CT X-ray carried out after a month postoperatively revealed the root canal treatment of the left femoral vein with a considerable decrease of the thrombosis of homolateral external iliac veins. Despite the endometriosis, it is uncommon in women who have reached menopause and must be considered in the differential diagnosis of pelvic masses.

Keywords

- Deep vein thrombosis - Endometriosis - Menopause

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Condition tags

endometriosis

MeSH descriptors

Endometriosis Postmenopause Retroperitoneal Space Venous Thrombosis Endometriosis Endometriosis Female Humans Middle Aged Overweight Retroperitoneal Space Venous Thrombosis Venous Thrombosis Venous Thrombosis

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Source provenance

europepmc
last seen: 2026-07-27T06:15:28.040536+00:00
openalex
last seen: 2026-06-10T17:14:06.276822+00:00
pubmed
last seen: 2026-05-13T22:20:37.704673+00:00
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