Segmental bowel resection for colorectal endometriosis: is there a correlation between histological pattern and clinical outcomes?

Mohamed Mabrouk, M Mabrouk, E Spagnolo, Emanuela Spagnolo, D Raimondo, Diego Raimondo, Antonietta D’Errico, A D'Errico, G Caprara, Greta Caprara, D Malvi, Deborah Malvi, F Catena, Fausto Catena, Giulia Ferrini, G Ferrini, Roberto Paradisi, R Paradisi, Renato Seracchioli, R Seracchioli
Human Reproduction · 2012 · vol. 27(5) , pp. 1314–1319 · doi:10.1093/humrep/des048 · PMID:22416007 · W2113805129
article OA: bronze CC0 ⤵ 62 in-corpus citations
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⚙ AI-generated summary by claude@2026-06, 2026-06-08 ⓘ

This study examined 47 patients undergoing laparoscopic colorectal endometriosis resection and found no correlation between histological patterns (satellite lesions, positive margins, vertical infiltration) and clinical outcomes like recurrence, pain, or quality of life.

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Abstract

BACKGROUND: Laparoscopic segmental resection as a treatment for intestinal endometriosis can be supported by favorable clinical outcomes, but carries a high risk of major complications. The purpose of this study is to evaluate histopathological patterns of colorectal endometriosis and investigate potential relationships between histological findings and clinical data. METHODS: We consecutively included 47 patients treated with laparoscopic segmental resection because of symptomatic colorectal endometriosis. All patients underwent follow-up for a median of 18 months (range: 6-35). We examined the histological patterns of colorectal endometriosis and evaluated the relationships between histological findings (satellite lesions, positive margins and vertical infiltration) and clinical outcomes (incidence of recurrence, quality of life and symptom improvement). Moreover, we observed if satellite lesions could influence preoperative scores of the short form-36 health survey (SF-36) questionnaire and visual analogue score (VAS) for pain symptoms. RESULTS: There were no statistically significant differences in terms of anatomical and pain recurrences, pain symptoms and quality of life improvement among patients with or without positive margins, satellite lesions and different degrees of vertical infiltration (P > 0.05). Furthermore, women with or without satellite lesions were no different in terms of preoperative VAS of pain symptoms and SF-36 scores (P > 0.05). CONCLUSIONS: The presence of satellite lesions or positive resection margins does not seem to influence clinical outcomes of segmental colorectal resection. Similarly, satellite lesions do not appear to have a major role in determining preoperative clinical presentation. These results may be useful to reconsider the surgical strategy for bowel endometriosis.

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Outcome instruments

VAS-pain

Condition tags

mesh:D004715endometriosisbowel_endometriosis

MeSH descriptors

Colonic Diseases Endometriosis Gastrointestinal Tract Rectal Diseases Colonic Diseases Colonic Diseases Endometriosis Endometriosis Female Follow-Up Studies Gastrointestinal Tract Humans Postoperative Complications Quality of Life Rectal Diseases Rectal Diseases Recurrence Treatment Outcome

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