How complete is full thickness disc resection of bowel endometriotic lesions? A prospective surgical and histological study

V Remorgida, Valentino Remorgida, Nicola Ragni, N Ragni, Simone Ferrero, S Ferrero, Paola Anserini, P Anserini, P Torelli, E Fulcheri, Ezio Fulcheri
Human Reproduction · 2005 · vol. 20(8) , pp. 2317–2320 · doi:10.1093/humrep/dei047 · PMID:15878923 · W2102548139
article OA: bronze CC0 ⤵ 158 in-corpus citations
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⚙ AI-generated summary by claude@2026-06, 2026-06-06 ⓘ

This study found that endometriosis infiltrated the bowel wall adjacent to the nodulectomy site in 43.8% of patients, indicating incomplete full thickness disc resection.

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Abstract

BACKGROUND: This study aims to evaluate the completeness of full thickness disc resection in the treatment of deep endometriotic bowel lesions. METHODS: This study comprised 16 women with bowel endometriotic lesions requiring segmental resection. For the purpose of the study, before intestinal resection, nodulectomy was performed. The presence of endometriotic infiltration in direct continuity with the removed nodule and the presence of fibrosis in the area surrounding the nodule were histologically evaluated. RESULTS: In seven out of 16 cases (43.8%; 95% CI, 19.8-70.1), endometriosis was found in the bowel wall adjacent to the site of nodulectomy; the infiltration was visible in the muscular layer in all cases. In cases of incomplete nodulectomy, the muscular layer of the bowel segment surrounding the endometriotic nodule contained limited or no fibrosis. CONCLUSIONS: Full thickness disc resection is not complete in > or =40% of women with bowel endometriosis. Our finding that fibrosis in the muscular layer, the main landmark during surgical resection, does not always surround bowel endometriotic lesions might explain why incomplete resection may occur.

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Condition tags

endometriosisbowel_endometriosis

MeSH descriptors

Endometriosis Endometriosis Intestinal Diseases Intestinal Diseases Adult Digestive System Surgical Procedures Digestive System Surgical Procedures Endometriosis Endometriosis Female Fibrosis Humans Intestinal Diseases Intestinal Diseases Intestines Intestines Intestines Laparoscopy Laparotomy Prospective Studies

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Papers in the corpus that this work cites (lower rings, blue) and that cite this one (upper rings, green). Dot size scales with the paper's in-corpus citation count — bigger dot = more influential within the endo/adeno field. Click a dot to open that paper. [ expand to 2 hops ] — adds papers reached through this work's immediate citers/citees. Heavier; up to 60 extra dots.

References (24)

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