A case of rectal endometriosis misdiagnosed as rectal malignancy on three colonoscopies and biopsies sharing a combined literature review

Jie Dong
In: Japanese journal of gastroenterology research · 2023 · vol. 3(7) · doi:10.52768/jjgastro/1160 · W4391149449
article OA: gold CC0
📄 Open PDF View on OpenAlex View at publisher
⚙ AI-generated summary by claude@2026-06, 2026-06-08 ⓘ

This case report describes endometriosis of the rectum misdiagnosed as malignancy on three separate colonoscopies and biopsies.

One-sentence paraphrase of the abstract; not a substitute for reading it. No clinical advice. How this works

⚙ AI-generated deep summary by claude@2026-06, 2026-06-09 ⓘ

This case report describes a 42-year-old woman with anal swelling and rectal/ sigmoid intestinal symptoms in whom intestinal endometriosis was repeatedly misdiagnosed as rectal malignancy after three colonoscopies and biopsies performed by different endoscopists. High-level evaluation included endoscopic findings with biopsies showing tubular adenoma with low-grade intraepithelial neoplasia, along with imaging that demonstrated a thickened, mass-like intestinal wall at the sigmoid–rectum junction without clear lymphadenopathy, leading clinicians to consider colon cancer and to perform surgical management. Despite intraoperative consideration of endometriosis during frozen section and subsequent pathological and immunohistochemical analysis (e.g., ER/PR positivity), the key limitation is that the evidence is limited to a single patient experience and the diagnostic narrative depends on interpretation across multiple procedures rather than a standardized comparative diagnostic framework. This paper is centrally about endometriosis — it reports rectal endometriosis misdiagnosed as rectal malignancy despite three colonoscopies and biopsies.

Read from the paper's body, not the abstract. Not a substitute for reading the paper. No clinical advice. How this works

Abstract

Endometriosis involves the intestine, and its clinical manifestations are nonspecific and lack of etiological manifestations. The diagnosis is difficult, which often leads to misdiagnosis. We report a case of endometriosis which was misdiagnosed as intestinal malignant tumor after colonoscopy and three biopsies.

My notes (saved in your browser only)

Condition tags

endometriosis

Citation neighborhood

Papers in the corpus that this work cites (lower rings, blue) and that cite this one (upper rings, green). Dot size scales with the paper's in-corpus citation count — bigger dot = more influential within the endo/adeno field. Click a dot to open that paper. [ expand to 2 hops ] — adds papers reached through this work's immediate citers/citees. Heavier; up to 60 extra dots.

References (48)

Source provenance

openalex
last seen: 2026-06-10T17:14:06.276822+00:00
License: CC0 · commercial use OK