ENDOMETRIOID ADENOCARCINOMA ARISING FROM ENDOMETRIOSIS OF THE RECTOSIGMOID

Shigeru Kobayashi, Morio Sasaki, Tatsuya Goto, Naoki Asakage, Masayuki Sekine, Takahisa Suzuki, Kenji Tsukada, Shigetaka Yamasaki, Shiro Ukawa
Digestive endoscopy : official journal of the Japan Gastroenterological Endoscopy Society · 2009 · vol. 22(1) , pp. 59–63 · doi:10.1111/j.1443-1661.2009.00925.x · PMID:20078668 · W1584871080
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⚙ AI-generated summary by claude@2026-06, 2026-06-08 ⓘ

This report details a case of endometrioid adenocarcinoma originating in rectosigmoid endometriosis, confirmed by histopathology and immunophenotype, potentially linked to prior hormone therapy.

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Abstract

A case of endometrioid adenocarcinoma supposedly arising from endometriosis of the rectum is reported. Malignant transformation is uncommon but a well-known complication of endometriosis. In the present case, it was proved by histopathological findings and immunophenotype such as cytokeratin7+/cytokeratin20-/estrogen receptor+. The cause of rectal endometriosis in this case might have been related with previously received hormone replacement therapy for ovarian endometriosis. Following surgical removal of the lesion, this patient underwent adjuvant chemotherapy with paclitaxel and carboplatin, although this kind of therapy is still controversial as to its effectiveness.

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Condition tags

endometriosis

MeSH descriptors

Adenocarcinoma Endometrial Neoplasms Endometriosis Rectal Diseases Sigmoid Diseases Adenocarcinoma Adenocarcinoma Colonoscopy Endometrial Neoplasms Endometrial Neoplasms Endometriosis Endometriosis Female Humans Middle Aged Ovarian Cysts Ovarian Cysts Rectal Diseases Rectal Diseases Sigmoid Diseases

Citation neighborhood

Papers in the corpus that this work cites (lower rings, blue) and that cite this one (upper rings, green). Dot size scales with the paper's in-corpus citation count — bigger dot = more influential within the endo/adeno field. Click a dot to open that paper. [ expand to 2 hops ] — adds papers reached through this work's immediate citers/citees. Heavier; up to 60 extra dots.

References (16)

Cited by (18)

Source provenance

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