An Unusual Rectosigmoid Mass: Endometrioid Adenocarcinoma Arising in Colonic Endometriosis: Case Report and Literature Review

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This case report describes a rare instance of endometrioid adenocarcinoma arising in colonic endometriosis, requiring immunohistochemistry for accurate diagnosis and surgical resection for treatment.

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Abstract

Malignant transformation is an infrequent complication of endometriosis. The ovary is the primary site in 79 per cent of cases, and extragonadal sites are identified in 21 per cent. Primary involvement of these types of tumors with the colon and/or rectum is a rare clinical entity. Endometrioid carcinoma is a common histologic type that remains a diagnostic challenge-the main differential diagnosis includes colorectal carcinomas. We report a case of malignant transformation arising in colonic endometriosis. The patient had a total abdominal hysterectomy and bilateral salpingo-oophorectomy 10 years before she presented with hematochezia. The patient was ultimately treated by surgical resection. Immunohistochemical staining in addition to the usual histopathology was critical for accurate diagnosis of this endometriosis-associated intestinal tumor.

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Condition tags

endometriosis

MeSH descriptors

Carcinoma, Endometrioid Colonic Diseases Endometriosis Rectal Neoplasms Sigmoid Neoplasms Carcinoma, Endometrioid Carcinoma, Endometrioid Carcinoma, Endometrioid Colonic Diseases Colonic Diseases Colonic Diseases Endometriosis Endometriosis Endometriosis Female Humans Middle Aged Rectal Neoplasms Rectal Neoplasms Rectal Neoplasms

Citation neighborhood

Papers in the corpus that this work cites (lower rings, blue) and that cite this one (upper rings, green). Dot size scales with the paper's in-corpus citation count — bigger dot = more influential within the endo/adeno field. Click a dot to open that paper. [ expand to 2 hops ] — adds papers reached through this work's immediate citers/citees. Heavier; up to 60 extra dots.

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Cited by (28)

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