Endometrial Adenocarcinoma Arising from Endometriosis of the Rectosigmoid Colon

Jones KD, Kevin D Jones, Kevin Jones, E R T C Owen, Owen E, Eoghan Owen, A Berresford, Ann Berresford, Berresford A, Christopher Sutton, Chris Sutton, Sutton C
Gynecologic oncology · 2002 · vol. 86(2) , pp. 220–222 · doi:10.1006/gyno.2002.6643 · PMID:12144831 · W2141718191
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⚙ AI-generated summary by claude@2026-06, 2026-06-07 ⓘ

This case report describes a rare instance of endometrial adenocarcinoma developing within endometriosis located in the rectosigmoid colon.

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Abstract

BackgroundOnly 21.3% of cases of malignant transformation of endometriosis occur at extragonadal pelvic sites. Forty cases of endometriosis-associated intestinal tumors are reported in the literature. Of these, 17 cases are primary adenocarcinomas arising in the rectosigmoid colon. In 8 of the 17 case reports the patients were using unopposed estrogen replacement therapy.CaseThe patient had previously undergone a total abdominal hysterectomy and bilateral salpingo-oophorectomy for deeply infiltrating rectovaginal endometriosis, and was using estrogen replacement therapy. She presented with rectal bleeding 12 years later, and a polyp was detected arising from the sigmoid colon. A biopsy detected malignant transformation of endometriosis to adenocarcinoma.ConclusionThis is the ninth case of a patient with this condition reported in the literature.

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Condition tags

endometriosis

MeSH descriptors

Adenocarcinoma Endometrial Neoplasms Endometriosis Rectal Diseases Sigmoid Diseases Adenocarcinoma Adenocarcinoma Adenocarcinoma Biopsy Endometrial Neoplasms Endometrial Neoplasms Endometrial Neoplasms Endometriosis Female Humans Laparotomy Middle Aged Rectal Diseases Sigmoid Diseases

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Papers in the corpus that this work cites (lower rings, blue) and that cite this one (upper rings, green). Dot size scales with the paper's in-corpus citation count — bigger dot = more influential within the endo/adeno field. Click a dot to open that paper. [ expand to 2 hops ] — adds papers reached through this work's immediate citers/citees. Heavier; up to 60 extra dots.

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Cited by (50)

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