Pathologic Characteristics of Bowel Endometriosis

The term “bowel endometriosis” should be used when endometrial-like glands and stroma infiltrate the bowel wall reaching at least the muscularis propria; endometriotic lesions infiltrating only the intestinal serosa should be considered peritoneal endometriosis. Because of the fibrosis present within the muscularis propria, bowel endometriosis causes wall thickening associated to luminal stenosis; smooth muscle hyperplasia is often present. Endometriosis can seldom produce pseudopolyps bulging into the visceral lumen. Bowel endometriotic foci may develop as a single main mass with small satellite lesions (multifocal disease) it or as multiple isolated nodules located in different bowel segments (multicentric disease). The histopathological appearance of bowel endometriosis is usually similar to that of other sites (endometrioid glands surrounded by stromal cells). The histological diagnosis of endometriosis is routinely accomplished on hematoxylin-eosin-stained sections; an immunohistochemical staining (cytokeratin 7, CA 125, CD10, PAX8, and steroid hormones receptors) may be used to confirm the diagnosis in unusual sites. Access this chapter Tax calculation will be finalised at checkout Purchases are for personal use only Similar content being viewed by others

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Author information Authors and Affiliations Corresponding author Editor information Editors and Affiliations Rights and permissions Copyright information © 2020 Springer Nature Switzerland AG About this chapter Cite this chapter Vellone, V.G., Biatta, C.M., Paudice, M., Barra, F., Ferrero, S., Scaglione, G. (2020). Pathologic Characteristics of Bowel Endometriosis. In: Ferrero, S., Ceccaroni, M. (eds) Clinical Management of Bowel Endometriosis. Springer, Cham. https://doi.org/10.1007/978-3-030-50446-5_3 Download citation DOI: https://doi.org/10.1007/978-3-030-50446-5_3 Published: Publisher Name: Springer, Cham Print ISBN: 978-3-030-50445-8 Online ISBN: 978-3-030-50446-5 eBook Packages: MedicineMedicine (R0)