Endometriosis as a Risk Factor for Colorectal Cancer

Víctor Manuel Vargas Hernández
In: World Journal of Gynecology & Womens Health · 2020 · vol. 3(2) · doi:10.33552/wjgwh.2020.03.000560 · W3008249816
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⚙ AI-generated summary by claude@2026-06, 2026-06-08 ⓘ

This review examines endometriosis as a benign disease with potential associations to malignancy, particularly colorectal cancer, noting diagnostic challenges and genetic factors.

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Abstract

Endometriosis is a common benign disease in women of reproductive age, it has been associated with an increased risk of various malignancies that is defined by certain histological criteria mainly 80% in ovary and 20% in extragonadal sites such as intestine, rectovaginal septum, abdominal wall , pleura and others; the greatest risk for colorectal cancer is women with adenomyosis or endometriosis; Several genetic alterations have been found in the risk of endometriosis associated with cancer; The symptomatology, imaging and endoscopic characteristics simulate other inflammatory and malignant lesions that make the preoperative diagnosis of extragonadal endometriosis difficult. This is a review of the knowledge about endometriosis and its potential risk of malignancy, particularly with colorectal cancer.

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Condition tags

endometriosisadenomyosis

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Papers in the corpus that this work cites (lower rings, blue) and that cite this one (upper rings, green). Dot size scales with the paper's in-corpus citation count — bigger dot = more influential within the endo/adeno field. Click a dot to open that paper. [ expand to 2 hops ] — adds papers reached through this work's immediate citers/citees. Heavier; up to 60 extra dots.

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