Endometrioid adenocarcinoma arising from colonic endometriosis in a Lynch syndrome patient

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This case report describes an instance of endometrioid adenocarcinoma originating from colonic endometriosis in a patient diagnosed with Lynch syndrome.

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This paper reports a case of endometrioid adenocarcinoma arising from colonic endometriosis in a patient with Lynch syndrome. The report describes the clinical and diagnostic context leading to identification of the malignancy associated with endometriosis in the colon, framed within the patient’s underlying hereditary cancer risk. A key limitation is that, as a single-case report with minimal methodological detail, it cannot establish incidence, mechanisms, or generalizable risk estimates. This paper is centrally about endometriosis — it documents malignant transformation of colonic endometriosis into endometrioid adenocarcinoma in a Lynch syndrome patient.

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Acknowledgments This study was supported by research grant NCKUH 96–075 from the National Cheng Kung University Hospital, Taiwan, Republic of China. Conflict of interest statement None. Author information Authors and Affiliations Corresponding author Rights and permissions About this article Cite this article Chen, PC., Chao, SC., Hsu, KF. et al. Endometrioid adenocarcinoma arising from colonic endometriosis in a Lynch syndrome patient. Int J Colorectal Dis 27, 681–682 (2012). https://doi.org/10.1007/s00384-011-1267-8 Accepted: Published: Issue date: DOI: https://doi.org/10.1007/s00384-011-1267-8

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Condition tags

mesh:D004715endometriosis

MeSH descriptors

Carcinoma, Endometrioid Colonic Diseases Colonic Neoplasms Colorectal Neoplasms, Hereditary Nonpolyposis Endometriosis Carcinoma, Endometrioid Colonic Diseases Colonic Neoplasms Colorectal Neoplasms, Hereditary Nonpolyposis Endometriosis Female Humans Middle Aged Neoplasm Invasiveness

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europepmc
last seen: 2026-06-04T01:30:01.192114+00:00
openalex
last seen: 2026-06-04T00:00:01.174412+00:00
pubmed
last seen: 2026-05-13T22:16:42.478857+00:00
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