Hormonal Treatment of Bowel Endometriosis

Simone Ferrero, Fabio Barra, Alessandro Loddo, Erkut Attar
In: Clinical Management of Bowel Endometriosis · 2020 · pp. 187–197 · doi:10.1007/978-3-030-50446-5_16 · W3083609497
book-chapter OA: closed CC0 ⤵ 1 in-corpus citation
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⚙ AI-generated summary by claude@2026-06+body, 2026-06-07 ⓘ

Progestins and combined estroprogestin therapies are safe and effective for bowel endometriosis symptoms, while GnRH agonists and AIs offer benefits but have significant side effects.

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⚙ AI-generated deep summary by claude@2026-06, 2026-06-07 ⓘ

This chapter reviews hormonal treatment options for bowel endometriosis, focusing on how therapies affect pain and intestinal complaints in women with bowel involvement, including progestins, combined estrogen-progestin regimens, GnRH agonists, and aromatase inhibitors, and discusses the need for monitoring during long-term use. It reports that hormonal therapies can improve symptoms in about two-thirds of women, that progestins and combined estroprogestins are efficacious and generally well tolerated, and that GnRH-a and aromatase inhibitors can improve symptoms but have adverse effects that limit long-term use. A key caveat is that intestinal nodules may progress despite therapy, and relief is temporary with symptoms often recurring within months after discontinuation, so treatments are described as not definitively curative. This paper is centrally about endometriosis — it specifically addresses hormonal treatment approaches for bowel endometriosis.

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endometriosisbowel_endometriosis

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