Impact of osteopathic manipulative therapy on quality of life of patients with deep infiltrating endometriosis with colorectal involvement: results of a pilot study

Camille Daraï, Daraï C, Olivier Deboute, Deboute O, Zacharopoulou C, Chrysoula Zacharopoulou, Laas E, Enora Laas, Geoffroy Canlorbe, Canlorbe G, J. Belghiti, Belghiti J, Jéremie Belghiti, Zilberman S, Sonia Zilberman, Marcos Ballester, Ballester M, Emile Daraï, Daraï E, Émile Daraï
European journal of obstetrics, gynecology, and reproductive biology · 2015 · vol. 188 , pp. 70–73 · doi:10.1016/j.ejogrb.2015.03.001 · PMID:25796057 · W2095268884
article OA: closed CC0 ⤵ 21 in-corpus citations
View on OpenAlex View on PubMed View at publisher
⚙ AI-generated summary by gemini-2.5-flash-lite, 2026-06-08 ⓘ

This pilot study investigated the impact of osteopathic manipulative therapy on the quality of life for patients suffering from deep infiltrating endometriosis affecting the colon and rectum.

One-sentence paraphrase of the abstract; not a substitute for reading it. No clinical advice. How this works

Abstract

ObjectiveA prospective pilot study to evaluate the potential role of osteopathic manipulative therapy (OMT) on quality of life (QOL) of patients with Deep Infiltrating Endometriosis (DIE) and colorectal involvement.Study designTwenty patients with DIE and colorectal infiltration completed the SF-36 QOL questionnaire before and after undergoing OMT.ResultsThe median age (range) of the patients was 30.4 years (22-39). Thirty-five percent of the patients had undergone previous surgery for endometriosis and 70% were on medical treatment. Fifteen of the 20 patients (75%) completed the protocol. There was no difference in the epidemiological characteristics or in the pre-OMT Physical Component Summary (PCS) and Mental Component Summary (MCS) of the SF-36 questionnaire between patients who completed the protocol or not. After a mean period of 24 days (15-53), a significant improvement in PCS (p=0.03) and MCS (p=0.0009) compared to pre-OMT values was observed giving a success rate of 80% and 60% in intention-to-treat, respectively.ConclusionOur results support that OMT can improve QOL of patients with DIE and colorectal involvement. Moreover, this pilot study can serve to determine power calculations for future randomized trials.

My notes (saved in your browser only)

Condition tags

endometriosisdie_deep_infiltrating

MeSH descriptors

Colonic Diseases Endometriosis Manipulation, Osteopathic Quality of Life Rectal Diseases Adult Colonic Diseases Colonic Diseases Endometriosis Endometriosis Female Humans Intention to Treat Analysis Magnetic Resonance Imaging Pilot Projects Prospective Studies Rectal Diseases Rectal Diseases Surveys and Questionnaires Ultrasonography

Citation neighborhood

Papers in the corpus that this work cites (lower rings, blue) and that cite this one (upper rings, green). Dot size scales with the paper's in-corpus citation count — bigger dot = more influential within the endo/adeno field. Click a dot to open that paper. [ expand to 2 hops ] — adds papers reached through this work's immediate citers/citees. Heavier; up to 60 extra dots.

References (40)

Cited by (21)

Source provenance

europepmc
last seen: 2026-09-04T06:17:57.233406+00:00
openalex
last seen: 2026-06-10T17:14:06.276822+00:00
pubmed
last seen: 2026-05-13T22:17:58.238279+00:00
License: CC0 · commercial use OK