The effect of psychotherapeutic interventions on pain and quality of life in endometriosis: a systematic review and meta-analysis study

meta-analysis OA: gold CC0
AI-generated summary by claude@2026-06, 2026-06-10

This systematic review and meta-analysis found that psychotherapeutic interventions significantly improved quality of life for women with endometriosis, though no significant effects were observed for pain or overall health profile.

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AI-generated deep summary by claude@2026-06, 2026-06-10

This systematic review and meta-analysis evaluated randomized controlled trials in women diagnosed with endometriosis, assessing whether psychotherapeutic interventions (e.g., yoga, hypnotherapy, mindfulness-based therapy, and other non-pharmacologic or related approaches) affected pain, quality of life, and health profile, using database searches conducted between August and October 2024 and including 10 eligible studies. Across included studies, psychotherapeutic interventions improved quality of life (SMD = 0.515, 95% CI = 0.035 to 0.995), while effects on pain and health profile were not statistically significant in the pooled estimates, and subgroup analyses suggested intervention type was not effective but number of sessions was. The authors report substantial heterogeneity for pain outcomes (I² = 84.463%), and the available trials limited certainty for some outcomes. This paper is centrally about endometriosis — it systematically analyzes psychotherapeutic interventions’ effects on endometriosis-related pain and quality of life.

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Abstract

AIM: This study aimed to determine the effect of psychotherapeutic interventions on pain, quality of life and health profile in women diagnosed with endometriosis. METHODS: For this systematic review and meta-analysis study, studies were obtained by searching PubMed, Web of Science, EBSCOhost, Google Scholar, and YÖK Thesis Center databases between August and October 2024 without any year limitation. After the review, 10 studies were included in the study. The data were synthesized by meta-analysis and narrative methods. RESULTS: In this systematic review and meta-analysis, psychotherapeutic interventions for the treatment and management of endometriosis were found to be effective on quality of life (SMD = 0.515, 95% CI = 0.035 to 0.995; Z = 2.104, I2 = 67.523%, p  0.05), and health profile (SMD = 0.041, 95% CI =  - 0.363 to 0.281; Z =  - 0.250759, I2 = 56.876%, p > 0.05). In subgroup analyses, it was determined that the types of psychotherapeutic interventions were not effective, but the number of sessions was effective. CONCLUSION: Psychotherapeutic interventions to reduce symptoms in endometriosis are effective in improving quality of life but not pain and health profile.

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Outcome instruments

EHP-30 VAS-pain NRS-pain

Condition tags

endometriosis

MeSH descriptors

Endometriosis Endometriosis Endometriosis Endometriosis Endometriosis Endometriosis Endometriosis Endometriosis Endometriosis Endometriosis Endometriosis Endometriosis Endometriosis Endometriosis Endometriosis Endometriosis Endometriosis Endometriosis Endometriosis Endometriosis

Citation neighborhood

Papers in the corpus that this work cites (lower rings, blue) and that cite this one (upper rings, green). Dot size scales with the paper's in-corpus citation count — bigger dot = more influential within the endo/adeno field. Click a dot to open that paper. [ expand to 2 hops ] — adds papers reached through this work's immediate citers/citees. Heavier; up to 60 extra dots.

References (24)

Source provenance

europepmc
last seen: 2026-06-15T06:13:43.845377+00:00
openalex
last seen: 2026-06-10T17:14:06.276822+00:00
pmc
last seen: 2026-05-13T20:22:03.195721+00:00
pubmed
last seen: 2026-06-15T06:10:24.760277+00:00
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