Benefits of physical therapy in improving quality of life and pain associated with endometriosis: A systematic review and meta-analysis

Rebeca Abril-Coello, Rebeca Abril‐Coello, Marta Correyero-León, Marta Correyero‐León, Luis Ceballos-Laita, Luis Ceballos‐Laita, Sandra Jiménez-Barrio, Sandra Jiménez‐Barrio
International Journal of Gynecology & Obstetrics · 2022 · vol. 162(1) , pp. 233–243 · doi:10.1002/ijgo.14645 · PMID:36571475 · W4312195610
meta-analysis OA: closed CC0 ⤵ 25 in-corpus citations
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⚙ AI-generated summary by claude@2026-06, 2026-06-04 ⓘ

This systematic review and meta-analysis found that non-pharmacologic conservative therapies significantly improved pain intensity and physical function in women with endometriosis compared to placebo.

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Abstract

OBJECTIVE: To assess whether non-pharmacologic conservative therapeutic interventions are beneficial in improving pain intensity and quality of life in women with endometriosis compared with placebo. METHODS: A systematic review with meta-analysis was designed. A literature search was performed in the following databases: PubMed, PEDro, Embase, CINAHL, Isi Web of Science, Enfispo, and Cochrane. Randomized controlled trials included women with endometriosis treated with conservative treatment versus placebo. The quality of the studies was assessed using the PEDro scale, and the risk of bias of the individual studies was assessed using the Cochrane Risk of Bias tool. For the overall quality of the studies, the GRADE guidelines were used. RESULTS: Meta-analysis included six studies. Significant results were obtained for pain intensity (standardized mean difference [SMD] -0.89; 95% confidence interval [CI] -1.21 to -0.57; I2 69%) and concerning quality of life, significant results were only obtained for the sub-variable physical function (SMD -1.49; 95% CI -2.88 to -0.10; I2 95%). No statistically significant differences were found for the rest of the variables analyzed. CONCLUSION: Non-pharmacologic conservative therapies are a therapeutic option for women with endometriosis for improving pain intensity and physical function.

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Condition tags

endometriosis

MeSH descriptors

Endometriosis Endometriosis Endometriosis Endometriosis Endometriosis Endometriosis Endometriosis Endometriosis Endometriosis Endometriosis Endometriosis Endometriosis Endometriosis Endometriosis Quality of Life Quality of Life Quality of Life Quality of Life Quality of Life Quality of Life

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Papers in the corpus that this work cites (lower rings, blue) and that cite this one (upper rings, green). Dot size scales with the paper's in-corpus citation count — bigger dot = more influential within the endo/adeno field. Click a dot to open that paper. [ expand to 2 hops ] — adds papers reached through this work's immediate citers/citees. Heavier; up to 60 extra dots.

References (32)

Cited by (26)

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