Impact of osteopathic manipulative therapy on quality of life of patients with deep infiltrating endometriosis with colorectal involvement: results of a pilot study

Camille Daraï, Daraï C, Olivier Deboute, Deboute O, Zacharopoulou C, Chrysoula Zacharopoulou, Laas E, Enora Laas, Geoffroy Canlorbe, Canlorbe G, J. Belghiti, Belghiti J, Jéremie Belghiti, Zilberman S, Sonia Zilberman, Marcos Ballester, Ballester M, Emile Daraï, Daraï E, Émile Daraï
European journal of obstetrics, gynecology, and reproductive biology · 2015 · vol. 188 , pp. 70–73 · doi:10.1016/j.ejogrb.2015.03.001 · PMID:25796057 · W2095268884
Non-randomised trial OA: closed CC0 ⤵ 21 in-corpus citations
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This pilot study investigated the impact of osteopathic manipulative therapy on the quality of life for patients suffering from deep infiltrating endometriosis affecting the colon and rectum.

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Abstract

OBJECTIVE: A prospective pilot study to evaluate the potential role of osteopathic manipulative therapy (OMT) on quality of life (QOL) of patients with Deep Infiltrating Endometriosis (DIE) and colorectal involvement. STUDY DESIGN: Twenty patients with DIE and colorectal infiltration completed the SF-36 QOL questionnaire before and after undergoing OMT. RESULTS: The median age (range) of the patients was 30.4 years (22-39). Thirty-five percent of the patients had undergone previous surgery for endometriosis and 70% were on medical treatment. Fifteen of the 20 patients (75%) completed the protocol. There was no difference in the epidemiological characteristics or in the pre-OMT Physical Component Summary (PCS) and Mental Component Summary (MCS) of the SF-36 questionnaire between patients who completed the protocol or not. After a mean period of 24 days (15-53), a significant improvement in PCS (p=0.03) and MCS (p=0.0009) compared to pre-OMT values was observed giving a success rate of 80% and 60% in intention-to-treat, respectively. CONCLUSION: Our results support that OMT can improve QOL of patients with DIE and colorectal involvement. Moreover, this pilot study can serve to determine power calculations for future randomized trials.

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Condition tags

endometriosisdie_deep_infiltrating

MeSH descriptors

Colonic Diseases Endometriosis Manipulation, Osteopathic Manipulation, Osteopathic Quality of Life Quality of Life Rectal Diseases Adult Adult Colonic Diseases Colonic Diseases Colonic Diseases Endometriosis Endometriosis Endometriosis Female Female Humans Humans Intention to Treat Analysis

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