Intérêt clinique du traitement ostéopathique chez les patientes ayant une endométriose colorectale : classification fondée sur les symptômes et la qualité de vie

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Osteopathic manipulative therapy improved quality of life and gynecological, digestive, and general symptoms in patients with colorectal endometriosis, with four symptom-based profiles identified based on treatment gain.

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Abstract

ObjectivesA prospective study to evaluate the clinical impact of osteopathic manipulative therapy (OMT) on symptoms and quality of life (QOL) of patients with colorectal endometriosis.MethodsForty-six patients with colorectal endometriosis completed the SF-36 QOL and symptoms questionnaire before and after OMT. A comparison and clustering analysis was performed to identify subgroups of patient's profile and symptom classification.ResultsThe mean age of the patients was 32±6.2 years. Prior surgery for endometriosis was recorded in 73.9 % of cases but none for deep infiltrating endometriosis. About three-quarters of the patients were nulliparous. The time between pre- and post-OMT completion of questionnaires was 28 days (15-63), A significant improvement in SF-36 QOL physical component summary (P<0.001) and mental component summary (P<0.001) was observed after OMT. Similarly, a significant improvement in gynecological, digestive and general symptoms values was observed. A clustering analysis allowed to identify four profiles of patients with colorectal endometriosis based on symptoms and a respective OMT gain of 30 %, 60 %, 64 % et 45 %.ConclusionsOur results support that OMT improve QOL and endometriosis symptoms of patients with colorectal endometriosis. Moreover, this symptom classification based on OMT gain can serve to design future randomized trial.

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Condition tags

endometriosis

MeSH descriptors

Colorectal Neoplasms Endometriosis Manipulation, Osteopathic Quality of Life Adult Colorectal Neoplasms Endometriosis Female Humans Prospective Studies

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