Risk factors for ovarian endometrioma recurrence following surgical excision: a systematic review and meta‑analysis

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AI-generated summary by claude@2026-06+body, 2026-06-08

This meta-analysis found age at surgery, CA125 level, cyst size, dysmenorrhea, endometriosis surgery history, pre-operative medication, and rASRM score to be risk factors for endometrioma recurrence, while post-operative pregnancy was protective.

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AI-generated deep summary by claude@2026-06, 2026-06-08

This systematic review and meta-analysis evaluated studies published before October 2020 to identify risk factors for ovarian endometrioma (OMA) recurrence after surgical excision, searching PubMed, Embase, the Cochrane Library, CNKI, and Wanfang and pooling odds ratios or standard mean differences. Across included evidence, recurrence was associated with younger/older age at surgery (SMD −0.28), higher CA125 level (SMD 0.51), larger cyst size (SMD 0.35), dysmenorrhea (OR 1.47), history of endometriosis-related surgery (OR 2.60), pre-operative medication (OR 2.13), and higher rASRM score (SMD 0.33), while post-operative pregnancy showed a protective association (OR 0.22). A key limitation noted in the paper is that the effects of bilateral involvement, coexisting adenomyosis, and post-operative medication on recurrence require further investigation. This paper is centrally about endometriosis — it specifically meta-analyzes predictors of ovarian endometrioma recurrence after excision, directly relevant to endometriosis outcomes.

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Condition tags

dysmenorrheaendometriosisendometrioma

MeSH descriptors

Endometriosis Laparoscopy Ovarian Diseases Dysmenorrhea Dysmenorrhea Endometriosis Endometriosis Female Humans Laparoscopy Neoplasm Recurrence, Local Ovarian Diseases Ovarian Diseases Pregnancy Recurrence Risk Factors Treatment Outcome

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Cited by (19)

Source provenance

europepmc
last seen: 2026-06-11T06:19:48.454388+00:00
openalex
last seen: 2026-06-10T17:14:06.276822+00:00
pubmed
last seen: 2026-05-13T22:24:31.988741+00:00
unpaywall
last seen: 2026-06-02T02:00:03.124865+00:00
License: CC0 · commercial use OK