New developments in the medical treatment of endometriosis

Mohamed A. Bedaiwy; Alfaraj S; Sukinah Alfaraj; Paul J. Yong; Paul Yong; Robert Casper; Robert F. Casper; Casper R

doi:10.1016/j.fertnstert.2016.12.025

New developments in the medical treatment of endometriosis

Mohamed A. Bedaiwy, Alfaraj S, Sukinah Alfaraj, Paul J. Yong, Paul Yong, Robert Casper, Robert F. Casper, Casper R

Fertility and sterility · 2017 · vol. 107(3) , pp. 555–565 · doi:10.1016/j.fertnstert.2016.12.025 · PMID:28139238 · W2582275704

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⚙ AI-generated summary by claude@2026-06, 2026-06-06 ⓘ

This paper reviews recent advancements in medical therapies for endometriosis, discussing novel pharmacological approaches and their clinical implications.

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Abstract

Endometriosis affects 1 in 10 women of reproductive-age. The current treatments are surgical and hormonal but have limitations, including the risk of recurrence, side effects, contraceptive action for women who desire pregnancy, and cost. New treatments include gonadotropin-releasing hormone analogues, selective progesterone (or estrogen) receptor modulators, aromatase inhibitors, immunomodulators, and antiangiogenic agents. Further research is needed into central sensitization, local neurogenesis, and the genetics of endometriosis to identify additional treatment targets. A wider range of medical options allows for the possibility of precision health and a more personalized treatment approach for women with endometriosis.

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Condition tags

endometriosis

MeSH descriptors

Angiogenesis Inhibitors Aromatase Inhibitors Contraceptives, Oral, Hormonal Endometriosis Endometrium Immunologic Factors Angiogenesis Inhibitors Angiogenesis Inhibitors Animals Aromatase Inhibitors Aromatase Inhibitors Contraceptives, Oral, Hormonal Contraceptives, Oral, Hormonal Endometriosis Endometriosis Endometriosis Endometrium Endometrium Endometrium Female

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Papers in the corpus that this work cites (lower rings, blue) and that cite this one (upper rings, green). Dot size scales with the paper's in-corpus citation count — bigger dot = more influential within the endo/adeno field. Click a dot to open that paper. [ expand to 2 hops ] — adds papers reached through this work's immediate citers/citees. Heavier; up to 60 extra dots.

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Cited by (50)

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