Robert F. Casper

ObjectiveTo evaluate whether the change in endometrial thickness between the end of the estrogen phase and the day of embryo transfer has an impact on the pregnancy rate in frozen-thawed embryo transfer (FET) cycles.DesignRetrospective obse…

ObjectifAméliorer la compréhension de l'endométriose et fournir une directive clinique factuelle pour ce qui est du diagnostic et de la prise en charge de l'endométriose.IssuesParmi les issues évaluées, on trouve les effets de la prise en c…

In this views and reviews series of articles, we focus on the long-term medical management of endometriosis in lieu of surgery. The development of noninvasive biomarkers will facilitate the early diagnosis of endometriosis and early medical…

Endometriosis affects 1 in 10 women of reproductive-age. The current treatments are surgical and hormonal but have limitations, including the risk of recurrence, side effects, contraceptive action for women who desire pregnancy, and cost. N…

For decades, combined estrogen-progestin oral contraceptive pills (OCPs) have been the first-line treatment for menstrual and pelvic pain associated with endometriosis without any clinical evidence of efficacy. Initial relief provided by OC…

The field of assisted reproductive technology is rapidly progressing with many new advances in the last decade. The present review discusses methods to improve oocyte quality in older women and new stimulation protocols that may improve the…

This issue of Fertility and Sterility contains four articles by the World Endometriosis Research Foundation whose present objective is global standardization of the collection of phenotypic data and biological samples, designated as the End…

Study objectiveExperience with low-dose intermittent danazol or prolonged gonadotropin-releasing hormone agonist (GnRH-a) with and without add-back therapy in endometriosis-associated ureteral obstruction.DesignRetrospective case series (Ca…

Fibrinolytics System Gene Polymorphisms and Endometriosis Risk: A Prospective Nested Case-Control Investigation from the Nurses’ Health Study II. Mohamed A. Bedaiwy, Dan Nayot, Stacey Missimer, Robert F. Casper. University Hospitals of Clev…

The physiologic importance of the endometrium in assisted reproductive technology is now receiving much research attention. The historical importance of ultrasound for determination of endometrial pattern, thickness and contractility is rev…

Objective To improve the understanding of endometriosis and to provide evidence-based guidelines for the diagnosis and management of endometriosis. Outcomes Outcomes evaluated include the impact of the medical and surgical management of end…

ObjectiveTo improve the understanding of endometriosis and to provide evidence-based guidelines for the diagnosis and management of endometriosis.OutcomesOUTCOMES evaluated include the impact of the medical and surgical management of endome…

MEDLINE, EMBASE, Scopus, and Web of Science databases literature search from inception to March 2009 was performed to identify published clinical trials and cohort, observational, and in vitro studies that evaluated the use of aromatase inh…

Background: Endometriosis is the presence of endometrial glandular and stromal cells outside of the uterine cavity. Our previous study showed that in vitro culture of human endometrial tissue in a three-dimensional (3D) fibrin matrix could …

Introduction: Endometriosis is the presence of endometrial glandular and stromal cells outside of the uterine cavity. This disease is found in about 10% of women of the reproductive age and in up to 50% of women with infertility. Surgery co…

This chapter discusses the potential role of the new group of medications called aromatase inhibitors in assisted reproduction. When an aromatase inhibitor is applied during controlled ovarian hyperstimulation (COO), estrogen production per…

This was a preliminary study to determine the effect of aromatase inhibitors in preventing the flare induced by GnRH agonist (GnRH-a) in women with endometriosis (n = 9) or leiomyomata (n = 4) who were given letrozole on the first 5 days of…

ObjectiveTo investigate the effects of an aromatase inhibitor, letrozole, on the growth of human endometrium in a three-dimensional fibrin matrix model of endometriosis.DesignExperimental study of human endometrial biopsies in a three-dimen…

Endometriosis is the presence of endometrial tissue outside of the uterine cavity and is the most common gynecologic disorder in women of reproductive age. Although the quality of life for women with endometriosis is severely compromised, v…