Risk factors for the development of ovarian endometrioma recurrence after surgical treatment in metropolitan areas
This retrospective study of 95 women found that younger age, lower BMI, higher CA-125, dyspareunia, and larger endometrioma size were associated with recurrence after ovarian endometrioma surgery, while hormonal contraception reduced recurrence risk.
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В ретроспективном когортном сравнительном исследовании 95 женщин, оперированных по поводу эндометриоидной кисты яичника (лапароскопическая цистэктомия) в 2018–2019 гг. в Екатеринбурге, оценивали анамнестические и клинико-лабораторные факторы, связанные с рецидивом после операции, с наблюдением и контрольным УЗИ не менее 12 мес; рецидив выявили у 13 (13,7%). В группе рецидива пациентки были моложе, имели более низкий ИМТ, а также статистически значимо более высокий уровень СА-125 после операции (медиана 42,7 vs 13,9 ед/мл), при этом значимые различия по числу антральных фолликулов после операции не обнаруживались. Среди факторов, ассоциированных с повышенными шансами рецидива, отмечены хроническая тазовая боль, мажущие кровянистые выделения вне менструации, дисменорея, диспареуния, двустороннее поражение, наличие аденомиоза и гипотиреоз; анализ также включал параметры назначения послеоперационной терапии (в частности, диеногеста и КОК), что было связано с различиями по частоте рецидивов. Ключевое ограничение, прямо вытекающее из дизайна: исследование выполнено на одной городской когорте и является ретроспективным, что ограничивает причинные выводы. This paper is centrally about endometriosis — it analyzes risk factors for recurrence of ovarian endometrioma after surgical treatment and includes adenomyosis among associated factors.
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