Treatment of Endometriosis

David L. Olive, D L Olive, Olive DL, E A Pritts, Elizabeth A. Pritts, Pritts EA
New England Journal of Medicine · 2001 · vol. 345(4) , pp. 266–275 · doi:10.1056/nejm200107263450407 · PMID:11474666 · W4252989508
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Endometriosis is the growth of uterine tissue outside the uterus, typically in the peritoneal cavity, causing pelvic pain and infertility, with deep implants being most painful.

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Abstract

Endometriosis is the growth of endometrium outside the uterine cavity or myometrium (endometriotic implants), usually in the peritoneal cavity (Figure 1). The question of how the tissue attains this abnormal placement is controversial, although the predominant theory is that retrograde menstruation is the cause.1 Additional factors that may be important in pathogenesis include immunologic abnormalities, endometrial disorders, and peritoneal dysfunction.1 The principal manifestations of endometriosis are pelvic pain and infertility.2 The extent of the pain is influenced primarily by the location and depth of the endometriotic implant, with deep implants in highly innervated areas most consistently associated with pain. Infertility . . .

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Condition tags

endometriosisinfertility

MeSH descriptors

Endometriosis Combined Modality Therapy Contraceptives, Oral Contraceptives, Oral Endometriosis Endometriosis Female Fertilization in Vitro Gonadotropin-Releasing Hormone Gonadotropin-Releasing Hormone Humans Infertility, Female Infertility, Female Infertility, Female Infertility, Female Ovulation Induction Pain Pain Pain Pain

Citation neighborhood

Papers in the corpus that this work cites (lower rings, blue) and that cite this one (upper rings, green). Dot size scales with the paper's in-corpus citation count — bigger dot = more influential within the endo/adeno field. Click a dot to open that paper. [ expand to 2 hops ] — adds papers reached through this work's immediate citers/citees. Heavier; up to 60 extra dots.

References (75)

Cited by (50)

Source provenance

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