The impact of endometriosis on the reproductive outcome of infertile patients

Inoue M, M. Inoue, Masato Inoue, Yoshimune Kobayashi, Kobayashi Y, Y. Kobayashi, Honda I, I. Honda, H. Awaji, Awaji H, A. Fujii, Fujii A
American journal of obstetrics and gynecology · 1992 · vol. 167(1) , pp. 278–282 · doi:10.1016/s0002-9378(11)91675-5 · PMID:1442943 · W2028433503
article OA: closed CC0 ⤵ 53 in-corpus citations
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This paper investigated how endometriosis affects pregnancy rates and live birth rates in infertile patients undergoing assisted reproductive technologies.

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Abstract

ObjectiveWe examined whether the presence and severity of endometriosis affect the reproductive outcome of infertile patients.Study designThe conception rates of 2080 infertile women, 1263 who had endometriosis and 817 who did not have endometriosis, were analyzed retrospectively by means of the chi 2 test. Depending on the stage of the disease patients who had endometriosis-associated infertility underwent expectant management, danazol therapy, or minor or major conservative surgery. The patients who failed to conceive after these conventional treatments were enrolled in the in vitro fertilization-embryo transfer program.ResultsThe conception rates were virtually identical regardless of the presence or absence of endometriosis (30.7% vs 30.0%). The outcome of in vitro fertilization-embryo transfer was not affected either by the presence or the severity of the disease.ConclusionEndometriosis had no impact on the reproductive outcome of infertile patients in this series unless the anatomy of the pelvic organs was heavily distorted, which can occur in the advanced stages of the disease.

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Condition tags

endometriosis

MeSH descriptors

Endometriosis Infertility, Female Infertility, Female Adult Danazol Danazol Electrocoagulation Embryo Transfer Endometriosis Endometriosis Female Fertilization in Vitro Humans Infertility, Female Pregnancy Retrospective Studies

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Papers in the corpus that this work cites (lower rings, blue) and that cite this one (upper rings, green). Dot size scales with the paper's in-corpus citation count — bigger dot = more influential within the endo/adeno field. Click a dot to open that paper. [ expand to 2 hops ] — adds papers reached through this work's immediate citers/citees. Heavier; up to 60 extra dots.

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