Endometriosis is not detrimental to embryo implantation in oocyte recipients

Linda Sung, L Sung, Tanmoy Mukherjee, T Mukherjee, Takeko Takeshige, T Takeshige, M Bustillo, María Bustillo, A B Copperman, Alan B. Copperman
Journal of assisted reproduction and genetics · 1997 · vol. 14(3) , pp. 152–156 · doi:10.1007/bf02766132 · PMID:9090558 · W2029528912
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⚙ AI-generated summary by claude@2026-06+body, 2026-06-08 ⓘ

This retrospective analysis of oocyte recipients found that endometriosis, regardless of severity, did not negatively impact pregnancy or implantation rates.

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⚙ AI-generated deep summary by claude@2026-06, 2026-06-10 · read from full text ⓘ

This retrospective study analyzed medical records of 239 consecutive oocyte-recipient patients treated from 1991 to 1995, comparing recipients with laparoscopically confirmed active endometriosis (n=55) to those without endometriosis (n=184). Within the endometriosis group, patients were subdivided by stage (mild stages I–II, n=18; moderate–severe stages III–IV, n=37) and outcomes were evaluated for implantation and pregnancy rates, along with baseline factors like recipient and donor age and endometrial thickness. The study found no significant differences in pregnancy rates (28% vs 29%) or implantation rates (12% vs 13%) between endometriosis and non-endometriosis groups, and no differences between mild and moderate–severe disease. A key caveat is that the analysis is limited to records from a defined historical period and is retrospective in design. This paper is centrally about endometriosis — specifically whether endometriosis in oocyte recipients affects embryo implantation and pregnancy rates in assisted reproduction.

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Abstract

Purpose: Our purpose was to determine the effects of endometriosis on implantation and pregnancy rates in ovum recipients.

Methods

The medical records of 239 consecutive oocyte recipient patients who were treated between January 1, 1991, and June 30, 1995, were analyzed retrospectively. Recipients with endometriosis (group I; n=55) were compared to recipients without endometriosis (group II; n=184). Patients in group I had active endometriotic disease confirmed by laparoscopy and were subdivided into mild (Stages I and II; n=18) and moderate to severe (Stages III and IV; n=37) endometriosis.

Results

No difference was found in recipient age, endometrial thickness, donor age, and embryos transferred. The pregnancy rates (28 versus 29%) and implantation rates (12 and 13%) were also comparable between group I and group II, as well as between patients with mild and patients with moderate to severe endometriosis.

Conclusions

The presence of endometriosis in oocyte recipients does not lower implantation or pregnancy rates. We conclude that the adverse effect of endometriosis on reproductive outcome is not related to implantation but, in fact, is most likely an effect on oocyte or embryo quality. Similar content being viewed by others

References

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Condition tags

mesh:D004715endometriosis

MeSH descriptors

Embryo Implantation Embryo Transfer Endometriosis Oocyte Donation Adult Age Factors Embryo Implantation Embryo Transfer Endometriosis Endometrium Endometrium Endometrium Female Fertilization in Vitro Fertilization in Vitro Humans Middle Aged Pregnancy Pregnancy Rate

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