Oxidative stress and oocyte quality: ethiopathogenic mechanisms of minimal/mild endometriosis-related infertility

Michele Gomes Da Broi, Paula Andrea Navarro
Cell and tissue research · 2015 · vol. 364(1) , pp. 1–7 · doi:10.1007/s00441-015-2339-9 · PMID:26685866 · W2208502322
review OA: green CC0 ⤵ 60 in-corpus citations
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⚙ AI-generated summary by claude@2026-06+body, 2026-06-08 ⓘ

This review explores how oxidative stress in the peritoneal, serum, and follicular microenvironments may impair oocyte quality and compromise fertility in women with minimal/mild endometriosis.

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⚙ AI-generated deep summary by claude@2026-06, 2026-06-08 ⓘ

This paper reviews mechanisms by which oxidative stress in peritoneal, serum, and/or follicular microenvironments may impair oocyte quality and thereby contribute to infertility in women with minimal or mild endometriosis. It synthesizes evidence linking oxidative stress to defects in oocyte cytoskeletal/spindle organization, altered redox balance, and compromised reproductive potential, emphasizing the oocyte as a key player in endometriosis-associated infertility. The main caveat is that it is a narrative review aimed at proposed etiopathogenic pathways rather than presenting new original experimental results. Relevance to endometriosis: the entire review is about endometriosis-related infertility mechanisms, specifically focusing on minimal/mild endometriosis and oxidative-stress–mediated oocyte quality impairment.

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Condition tags

mesh:D004715endometriosisinfertility

MeSH descriptors

Endometriosis Infertility, Female Oocytes Oxidative Stress Animals Endometriosis Endometriosis Female Humans Infertility, Female Infertility, Female Oocytes Oocytes

Citation neighborhood

Papers in the corpus that this work cites (lower rings, blue) and that cite this one (upper rings, green). Dot size scales with the paper's in-corpus citation count — bigger dot = more influential within the endo/adeno field. Click a dot to open that paper. [ expand to 2 hops ] — adds papers reached through this work's immediate citers/citees. Heavier; up to 60 extra dots.

References (68)

Cited by (50)

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