Comparative analysis of the spindle and chromosome configurations of in vitro–matured oocytes from patients with endometriosis and from control subjects: a pilot study

Barcelos ID, Ionara D Barcelos, Ionara Diniz Evangelista Santos Barcelos, Vieira RC, Rodolpho Cruz Vieira, Rodolpho C Vieira, Elisa M. Ferreira, Evandro Maia Ferreira, Wellington P. Martins, Martins WP, Rui A Ferriani, Rui Alberto Ferriani, Ferriani RA, Paula Andrea Navarro, Paula A Navarro
Fertility and sterility · 2009 · vol. 92(5) , pp. 1749–1752 · doi:10.1016/j.fertnstert.2009.05.006 · PMID:19523612 · W2151232196
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This pilot study compared spindle and chromosome configurations in in vitro-matured oocytes from endometriosis patients and control subjects, finding no significant differences between the groups.

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Abstract

Preliminary data from a prospective controlled study did not demonstrate an increased percentage of meiotic abnormalities for in vitro-matured oocytes obtained from stimulated cycles of endometriosis and control patients. However, the tendency toward a higher proportion of telophase I in apparently matured oocytes observed in endometriosis patients suggests an impairment or delay of the completion of meiosis I which requires further evaluation.

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Condition tags

endometriosis

MeSH descriptors

Chromosomes, Human Chromosomes, Human Chromosomes, Human Endometriosis Oocytes Ovarian Diseases Spindle Apparatus Adult Case-Control Studies Cells, Cultured Cytogenetic Analysis Endometriosis Endometriosis Endometriosis Female Humans Infertility, Female Infertility, Female Infertility, Female Infertility, Female

Citation neighborhood

Papers in the corpus that this work cites (lower rings, blue) and that cite this one (upper rings, green). Dot size scales with the paper's in-corpus citation count — bigger dot = more influential within the endo/adeno field. Click a dot to open that paper. [ expand to 2 hops ] — adds papers reached through this work's immediate citers/citees. Heavier; up to 60 extra dots.

References (34)

Cited by (47)

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