Comparative analysis of the spindle and chromosome configurations of in vitro-matured oocytes from patients with endometriosis and from control subjects: a pilot study

Barcelos ID, Ionara D Barcelos, Ionara Diniz Evangelista Santos Barcelos, Vieira RC, Rodolpho Cruz Vieira, Rodolpho C Vieira, Elisa M. Ferreira, Evandro Maia Ferreira, Wellington P. Martins, Martins WP, Rui A Ferriani, Rui Alberto Ferriani, Ferriani RA, Paula Andrea Navarro, Paula A Navarro
Fertility and sterility · 2009 · vol. 92(5) , pp. 1749–1752 · doi:10.1016/j.fertnstert.2009.05.006 · PMID:19523612 · W2151232196
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This pilot study compared spindle and chromosome configurations in in vitro-matured oocytes from endometriosis patients and control subjects, finding no significant differences between the groups.

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Abstract

Preliminary data from a prospective controlled study did not demonstrate an increased percentage of meiotic abnormalities for in vitro-matured oocytes obtained from stimulated cycles of endometriosis and control patients. However, the tendency toward a higher proportion of telophase I in apparently matured oocytes observed in endometriosis patients suggests an impairment or delay of the completion of meiosis I which requires further evaluation.

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Condition tags

endometriosis

MeSH descriptors

Chromosomes, Human Chromosomes, Human Chromosomes, Human Chromosomes, Human Endometriosis Oocytes Ovarian Diseases Spindle Apparatus Adult Adult Case-Control Studies Case-Control Studies Cells, Cultured Cells, Cultured Cytogenetic Analysis Cytogenetic Analysis Endometriosis Endometriosis Endometriosis Endometriosis

Citation neighborhood (2-hop)

Papers in the corpus that this work cites (lower rings, blue) and that cite this one (upper rings, green). Dot size scales with the paper's in-corpus citation count — bigger dot = more influential within the endo/adeno field. Click a dot to open that paper. Outer rings show 2-hop neighbours — papers reached through the immediate citers/citees. [ collapse to 1-hop ]

References (34)

Cited by (47)

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License: CC0 · commercial use OK