An overview of non-obstructive etiopathogenic mechanisms of endometriosis-related infertility

Bruno Ramalho de Carvalho, Hitomi Miura Nakagava, Adelino Amaral Silva, Antonio Cesar Paes Barbosa
In: JBRA Assisted Reproduction · 2010 · vol. 14(4) · doi:10.5935/1518-0557.2011.14.4.08 · W4320911290
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This paper reviews classic and recent non-obstructive theories for how endometriosis causes infertility, beyond mechanical obstruction, to aid in patient counseling.

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Abstract

Although up to 60% of women with endometriosis complain of infertility, knowledge on the etiopathogeny of such an association is still limited.Mechanical obstruction to reproductive processes is the most accepted phenomenon to explain infertility in women with endometriosis, but the diverse phenotypes of the disease and notorious biochemical changes in the pelvic-peritonial microenvironment lead us to a complex multifactorial net of possibly connected mechanisms.In this article, we revised classic and recently proposed non-obstructive etiopathogenic theories on endometriosis-related infertility, providing background to counseling and follow up of those patients in reproductive medicine clinics.

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endometriosisinfertility

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Papers in the corpus that this work cites (lower rings, blue) and that cite this one (upper rings, green). Dot size scales with the paper's in-corpus citation count — bigger dot = more influential within the endo/adeno field. Click a dot to open that paper. [ expand to 2 hops ] — adds papers reached through this work's immediate citers/citees. Heavier; up to 60 extra dots.

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