Evaluation of the effect of endometriosis on oocyte quality and endometrial environment by comparison of donor and recipient outcomes following embryo transfer in a shared oocyte program.

B Katsoff, Katsoff B, Check JH, J H Check, Davies E, E Davies, C. Wilson, Colin Wilson, Wilson C
Clinical and experimental obstetrics & gynecology · 2006 · vol. 33(4) , pp. 201–2 · PMID:17214020 · W2174077119
article OA: closed CC0 ⤵ 19 in-corpus citations
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This study compared embryo transfer outcomes in a shared oocyte program to evaluate endometriosis's impact on the uterine environment versus oocytes, finding no significant differences but a trend toward lower rates in women undergoing controlled ovarian hyperstimulation.

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Abstract

PURPOSE: To determine whether endometriosis has an effect on the uterine environment vs the oocyte itself. METHODS: A retrospective study comparing pregnancy outcome of infertile donors sharing oocytes with donor egg recipients according to whether the donor or recipient had endometriosis or not was carried out. RESULTS: There were 26 transfers from donors with endometriosis vs 144 in donors without endometriosis. The clinical and viable PRs and implantation rates were 42.9%, 38.1%, and 29.4% for the endometriosis group vs 60.9%, 51.9%, and 33.2%, respectively, for donors without endometriosis (p = NS). The clinical and viable PRs and implantation rates for donors with endometriosis per ET was 41.2%, 35.3%, and 20.4% vs 50.4%, 48.0% and 28.4% for donors without endometriosis, respectively (p = NS). CONCLUSIONS: Though no significant differences were found in donors with or without endometriosis in any parameters, there did appear to be a trend for lower PRs and implantation rates in women undergoing controlled ovarian hyperstimulation.

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Condition tags

endometriosis

MeSH descriptors

Endometriosis Oocytes Uterus Adult Embryo Transfer Endometriosis Female Humans Middle Aged Oocytes Pregnancy Pregnancy Rate Retrospective Studies Uterus

Citation neighborhood

Papers in the corpus that this work cites (lower rings, blue) and that cite this one (upper rings, green). Dot size scales with the paper's in-corpus citation count — bigger dot = more influential within the endo/adeno field. Click a dot to open that paper. [ expand to 2 hops ] — adds papers reached through this work's immediate citers/citees. Heavier; up to 60 extra dots.

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