Paula A Navarro

No ORCID on file · 11 papers in corpus
article 2021
Reproductive BioMedicine Online ·doi:10.1016/j.rbmo.2021.01.024

Research questionIs the transcriptome of cumulus cells of infertile women with advanced endometriosis (EIII/IV), with and without endometrioma, altered?DesignIn this prospective case-control study, next-generation RNA sequencing was used to…

article 2017
JBRA assisted reproduction ·doi:10.5935/1518-0557.20170038

OBJECTIVE: Alterations in endometrial receptivity may be involved in the etiopathogenesis of endometriosis-related infertility. The literature has suggested that patients with endometriosis present progestin resistance, which could affect e…

article 2017
Molecular reproduction and development ·doi:10.1002/mrd.22943

Early endometriosis is associated with infertility, and oxidative stress may play a role in the pathogenesis of disease‐related infertility. This prospective case‐control study aimed to compare the presence of oxidative stress markers in th…

article 2017
Reproductive BioMedicine Online ·doi:10.1016/j.rbmo.2017.06.021

A deleterious effect of endometriosis on oocyte quality has been proposed. Evidence suggests that cumulus cells could be used as indirect biomarkers of oocyte quality. The PTGS2 gene, which encodes cyclooxygenase 2 (COX-2), is deregulated i…

article 2017
Reproductive sciences (Thousand Oaks, Calif.) ·doi:10.1177/1933719117691142

Endometriosis is frequently associated with infertility and it is believed that the impairment of endometrial receptivity may be one of the mechanisms involved in this condition. Pinopodes are endometrial cycle-dependent structures that see…

article 2016
Cell and tissue research ·doi:10.1007/s00441-016-2428-4

Impaired oocyte quality and oxidative stress might be involved in the pathogenesis of endometriosis-related infertility. To improve our understanding of the role of oxidative stress in this condition, we compare eight oxidative stress marke…

article 2015
Reproductive BioMedicine Online ·doi:10.1016/j.rbmo.2015.01.012

Aromatase plays a fundamental role in the establishment of oocyte quality, which might be compromised in infertile women with endometriosis. The expression of the CYP19A1 gene (that encodes aromatase) was compared in cumulus cells and oestr…

article 2015
Reproductive sciences (Thousand Oaks, Calif.) ·doi:10.1177/1933719115602772

This study evaluated the potential protective effect of the antioxidants, l-carnitine (LC) and N-acetyl-cysteine (NAC), in preventing meiotic oocyte damage induced by follicular fluid (FF) from infertile women with mild endometriosis (ME). …

letter 2014
Human Reproduction ·doi:10.1093/humrep/deu310
other 2013
Reproductive sciences (Thousand Oaks, Calif.) ·doi:10.1177/1933719112459217

The objectives of this prospective study were to evaluate the nuclear maturation stage and the presence and location of meiotic spindles of in vivo matured oocytes from infertile women with and without endometriosis (male or tubal causes of…

article 2009
Fertility and sterility ·doi:10.1016/j.fertnstert.2009.05.006

Preliminary data from a prospective controlled study did not demonstrate an increased percentage of meiotic abnormalities for in vitro-matured oocytes obtained from stimulated cycles of endometriosis and control patients. However, the tende…